ArticleWorld journal of gastroenterology2009
Impact of age-related comorbidity on results of colorectal cancer surgery.
Article in World journal of gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Elderly patients over 80 years undergoing colorectal cancer resection: Development and validation of a predictive nomogram for survival.World journal of gastrointestinal surgery · 2023Article
- A 10-Year Evaluation of Short-Term Outcomes After Synchronous Colorectal Cancer Surgery: a Dutch Population-Based Study.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Article
- Predictors of 30-Day Mortality Among Dutch Patients Undergoing Colorectal Cancer Surgery, 2011-2016.JAMA network open · 2021Article
- Technical efficiency evaluation of colorectal cancer care for older patients in Dutch hospitals.PloS one · 2021Observational
- Low Socioeconomic Status Is Associated with Worse Outcomes After Curative Surgery for Colorectal Cancer: Results from a Large, Multicenter Study.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020Article
- The impact of comorbidities on post-operative complications following colorectal cancer surgery.PloS one · 2020Article
- E-PASS Scoring System May Be Useful for Prediction of Postoperative Complications in Super Elderly Colorectal Cancer Surgery Patients.Journal of the anus, rectum and colon · 2020Article
- Long-Term Survival in Octogenarians After Surgical Treatment for Colorectal Cancer: Prevention of Postoperative Complications is Key.Annals of surgical oncology · 2018Article
- Prognostic factors and hazard ratios in colorectal cancer patients over 80 years of age: a retrospective, 20-year, single institution review.Journal of gastrointestinal oncology · 2018Article
- Comorbidity and the risk of anastomotic leak in Chinese patients with colorectal cancer undergoing colorectal surgery.International journal of colorectal disease · 2017Article
- Article
- The Norwegian dietary guidelines and colorectal cancer survival (CRC-NORDIET) study: a food-based multicentre randomized controlled trial.BMC cancer · 2017Article
- Pulmonary Complications after Surgery for Rectal Cancer in Elderly Patients: Evaluation of Laparoscopic versus Open Approach from a Multicenter Study on 477 Consecutive Cases.Gastroenterology research and practice · 2017Article
- Complications and risk prediction in treatment of elderly patients with rectal cancer.International journal of colorectal disease · 2016Observational
- The association between comorbidities and the quality of life among colorectal cancer survivors in the People's Republic of China.Patient preference and adherence · 2016Article
- Outcomes of rectal cancer treatment--influence of age?International journal of colorectal disease · 2014Article
- Clinical characteristics and prognosis of young patients with colorectal cancer in Eastern China.World journal of gastroenterology · 2013Article
- The minimally invasive approach is associated with reduced perioperative thromboembolic and bleeding complications for patients receiving preoperative chronic oral anticoagulant therapy who undergo colorectal surgery.Surgical endoscopy · 2013Article
- Surgical treatment of colorectal cancer in patients aged over 80 years.International journal of colorectal disease · 2012Article
- Application of Petersen Index score for Dukes'B colorectal cancer in a population of 103 consecutive resected patients.Updates in surgery · 2012Article
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8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo analyze the correlation between preexisting comorbidity and other clinicopathological features, short-term surgical outcome and long-term survival in elderly patients with colorectal cancer (CRC).
methodsAccording to age, 403 patients operated on for CRC in our department were divided into group A (< 70 years old) and group B (> or = 70 years old) and analyzed statistically.
resultsRectal localization prevailed in group A (31.6% vs 19.7%, P = 0.027), whereas the percentage of R0 resections was 77% in the two groups. Comorbidity rate was 46.2% and 69.1% for group A and B, respectively (P < 0.001), with a huge difference as regards cardiovascular diseases. Overall, postoperative morbidity was 16.9% and 20.8% in group A and B, respectively (P = 0.367), whereas mortality was limited to group B (4.5%, P = 0.001). In both groups, patients who suffered from postoperative complications had a higher overall comorbidity rate, with preexisting cardiovascular diseases prevailing in group B (P = 0.003). Overall 5-year survival rate was significantly better for group A (75.2% vs 55%, P = 0.006), whereas no significant difference was observed considering disease-specific survival (76.3% vs 76.9%, P = 0.674).
conclusionIn spite of an increase in postoperative mortality and a lower overall long-term survival for patients aged > or = 70 years old, it should be considered that, even in the elderly group, a significant number of patients is alive 5 years after CRC resection.
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