ArticleJournal of traumatic stress2009
The role of the dopamine transporter (DAT) in the development of PTSD in preschool children.
Article in Journal of traumatic stress, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 78 citations in OpenAlex.
- Sex-dependent effects of short- and long-term social isolation on behavior and medial prefrontal DAT in rats.Scientific reports · 2026Article
- Article
- Review: Dopamine, Serotonin, and the Translational Neuroscience of Aggression in Autism Spectrum Disorder.JAACAP open · 2025Review
- Accumbal Dopamine Responses Are Distinct between Female Rats with Active and Passive Coping Strategies.Biomolecules · 2024Article
- Prominent genetic variants and epigenetic changes in post-traumatic stress disorder among combat veterans.Molecular biology reports · 2024Review
- Dopamine release at the time of a predicted aversive outcome causally controls the trajectory and expression of conditioned behavior.Cell reports · 2023Article
- Accelerated high frequency rTMS induces time-dependent dopaminergic alterations: a DaTSCAN brain imaging study in healthy beagle dogs.Frontiers in veterinary science · 2023Article
- Short-Term Consequences of Single Social Defeat on Accumbal Dopamine and Behaviors in Rats.Biomolecules · 2022Article
- Ventral Tegmental Area Dysfunction and Disruption of Dopaminergic Homeostasis: Implications for Post-traumatic Stress Disorder.Molecular neurobiology · 2021Review
- Dopamine transporter (DAT1) gene in combat veterans with PTSD: A case-control study.Psychiatry research · 2021Article
- DAT1 and Its Psychological Correlates in Children with Avoidant/Restrictive Food Intake Disorder: A Cross-Sectional Pilot Study.Behavioral sciences (Basel, Switzerland) · 2021Article
- Emotional-Behavioral Regulation, Temperament and Parent-Child Interactions Are Associated with Dopamine Transporter Allelic Polymorphism in Early Childhood: A Pilot Study.International journal of environmental research and public health · 2020Article
- Genetic and Neuroimaging Approaches to Understanding Post-Traumatic Stress Disorder.International journal of molecular sciences · 2020Review
- Rats Lacking Dopamine Transporter Display Increased Vulnerability and Aberrant Autonomic Response to Acute Stress.Biomolecules · 2020Article
- Children's DAT1 Polymorphism Moderates the Relationship Between Parents' Psychological Profiles, Children's DAT Methylation, and Their Emotional/Behavioral Functioning in a Normative Sample.International journal of environmental research and public health · 2019Article
- Imputation of behavioral candidate gene repeat variants in 486,551 publicly-available UK Biobank individuals.European journal of human genetics : EJHG · 2019Article
- Therapeutic Challenges of Post-traumatic Stress Disorder: Focus on the Dopaminergic System.Frontiers in pharmacology · 2019Review
- Research domain criteria and the study of trauma in children: Implications for assessment and treatment research.Clinical psychology review · 2018Review
- Genetic approaches for the study of PTSD: Advances and challenges.Neuroscience letters · 2017Review
- Posttraumatic Stress Disorder and Alcohol Use Disorder: A Critical Review of Pharmacologic Treatments.Alcoholism, clinical and experimental research · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Population-based association studies have supported the heritability of posttraumatic stress disorder (PTSD). This study explored the influence of genetic variation in the dopamine transporter (DAT) 3' untranslated region variable number tandem repeat on the development of PTSD in preschool children exposed to Hurricane Katrina, diagnosed using a developmentally appropriate semistructured interview. A diagnosis according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition , (DSM-IV; American Psychiatric Association, 1994), total symptoms, and specifically Criterion D symptoms were significantly more likely to be found in children with the 9 allele. This study replicates a previous finding in adults with PTSD. The specificity of this finding to the increased arousal symptoms of Criterion D suggests that dopamine and the DAT allele may contribute to one heritable path in a multifinality model of the development of PTSD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.