ReviewThe Journal of surgical research2011
Resuscitation-induced intestinal edema and related dysfunction: state of the science.
Review in The Journal of surgical research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Implementation and outcomes of enhanced recovery protocols in pediatric surgery: a systematic review and meta-analysis.Pediatric surgery international · 2022Pooled it
- Intraoperative Fluid Restriction in Pancreatic Surgery: A Double Blinded Randomised Controlled Trial.PloS one · 2015Trial
- From Microbiota Correction to Host Protection: A New Therapeutic Target for the Prevention and Treatment of Postoperative Complications.Journal of clinical medicine · 2026Review
- Glial Connexin-43 Is a Pathogenic Mechanism Promoting Gut Inflammation in Postoperative Ileus Induced by Gut Surgical Manipulation With Potential Relevance to Humans.Cellular and molecular gastroenterology and hepatology · 2026Article
- Perioperative fluid therapy impairs lymphatic pump function in male rats.Physiological reports · 2025Article
- Global research trends in postoperative ileus from 2011 to 2023: A scientometric study.World journal of gastrointestinal surgery · 2024Article
- A nomogram to predict prolonged postoperative ileus after intestinal resection for Crohn's disease.International journal of colorectal disease · 2022Article
- Intermittent boluses of balanced salt solution for post-operative intravenous hydration following elective major abdominal and thoracic surgery in children.Pediatric surgery international · 2022Article
- Impact of Early Fluid Balance on Long-Term Mortality in Critically Ill Surgical Patients: A Retrospective Cohort Study in Central Taiwan.Journal of clinical medicine · 2021Article
- Risk factors for upper and lower type prolonged postoperative ileus following surgery for Crohn's disease.International journal of colorectal disease · 2021Article
- Subtyping Hyperchloremia among Hospitalized Patients by Machine Learning Consensus Clustering.Medicina (Kaunas, Lithuania) · 2021Article
- Effect of intraoperative fluid volume on postoperative ileus after robot-assisted radical cystectomy.Scientific reports · 2021Article
- Effect of Feed Intake on Water Consumption in Horses: Relevance to Maintenance Fluid Therapy.Frontiers in veterinary science · 2021Review
- Risk Factors and Outcomes for Postoperative Ileus After Small Intestinal Fistula Excision in Patients With Diffuse Extensive Abdominal Adhesions.Frontiers in surgery · 2021Article
- Volume Resuscitation in the Acutely Hemorrhaging Patient: Historic Use to Current Applications.Frontiers in veterinary science · 2021Review
- Postoperative Ileus and Postoperative Gastrointestinal Tract Dysfunction: Pathogenic Mechanisms and Novel Treatment Strategies Beyond Colorectal Enhanced Recovery After Surgery Protocols.Frontiers in pharmacology · 2020Review
- In vivo performance of a visible wavelength optical sensor for monitoring intestinal perfusion and oxygenation.Journal of biomedical optics · 2018Article
- Impact of hypertonic saline on postoperative complications for patients undergoing upper gastrointestinal surgery.Medicine · 2017Observational
- Optimal Fluid Therapy for Traumatic Hemorrhagic Shock.Critical care clinics · 2017Review
- The incidence and risk factors for post-operative ileus after spinal fusion surgery: a multivariate analysis.International orthopaedics · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
High volume resuscitation and damage control surgical methods, while responsible for significantly decreasing morbidity and mortality from traumatic injuries, are associated with pathophysiologic derangements that lead to subsequent end organ edema and dysfunction. Alterations in hydrostatic and oncotic pressures frequently result in intestinal edema and subsequent dysfunction. The purpose of this review is to examine the principles involved in the development of intestinal edema, current and historical models for the study of edema, effects of edema on intestinal function (particularly ileus), molecular mediators governing edema-induced dysfunction, potential role of mechanotransduction , and therapeutic effects of hypertonic saline. We review the current state of the science as it relates to resuscitation induced intestinal edema and resultant dysfunction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.