ArticleAmerican heart journal2009
The impact of kidney transplantation on heart failure risk varies with candidate body mass index.
Article in American heart journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Management of obesity in kidney transplant candidates and recipients: A clinical practice guideline by the DESCARTES Working Group of ERA.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021Guideline
- Transient decline and early recovery of noninvasive myocardial work after kidney transplantation: a prospective study.Renal failure · 2025Article
- Chronic Kidney Disease in Patients With Heart Failure With a Preserved Ejection Fraction: The Underlying Role of Visceral Adiposity.Journal of the American College of Cardiology · 2025Review
- Practices in the management of kidney transplant candidates and recipients with obesity: A survey of United States transplant programs.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025Article
- Synergistic Integration of Multimodal Metabolic and Bariatric Interventions Transforming Transplant Care.Journal of clinical medicine · 2025Review
- Complexities and outcomes of pulmonary hypertension in kidney transplant patients: a comprehensive review.Turkish journal of nephrology · 2024Article
- Standardized risk-stratified cardiac assessment and early posttransplant cardiovascular complications in kidney transplant recipients.Frontiers in cardiovascular medicine · 2024Article
- The Diabetic Cardiorenal Nexus.International journal of molecular sciences · 2022Review
- An overview of frailty in kidney transplantation: measurement, management and future considerations.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020Review
- Induction immunosuppression agents as risk factors for incident cardiovascular events and mortality after kidney transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2019Article
- Clinical and Economic Consequences of Early Cancer After Kidney Transplantation in Contemporary Practice.Transplantation · 2017Article
- Clinical and economic consequences of first-year urinary tract infections, sepsis, and pneumonia in contemporary kidney transplantation practice.Transplant international : official journal of the European Society for Organ Transplantation · 2016Article
- Depression diagnoses after living kidney donation: linking U.S. Registry data and administrative claims.Transplantation · 2012Article
- Associations of pretransplant weight and muscle mass with mortality in renal transplant recipients.Clinical journal of the American Society of Nephrology : CJASN · 2011Article
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundThe relationship of body mass index (BMI) with heart failure (HF) risk before and after kidney transplant is not well described.
methodsWe examined United States Renal Data System records for 67,591 kidney transplant candidates (1995-2004) with Medicare insurance and BMI data at listing. Heart failure diagnoses were ascertained from Medicare billing claims. Body mass index was categorized per World Health Organization criteria. We modeled time-dependent associations (adjusted hazard ratio, aHR) of transplant with HF risk after listing compared with waiting in each BMI group by multivariable, stratified Cox regression. The time-dependent exposure variables partitioned relative risk of HF after transplant versus waiting into early (<or=90 days) and late (>90 days) posttransplant periods.
resultsThe BMI distribution of listed candidates was as follows: 3.7% under, 40.4% normal, 32.0% over, 16.2% obese, and 7.7% morbidly obese weight. The prevalence of HF among patients awaiting transplant reached 57.4% by 3 years. Deceased-donor transplant was associated with increased early HF risk compared with continued waiting-aHRs ranged from 2.23 for normal-BMI to 2.82 for morbidly obese patients. However, transplant reduced the risk of HF in the late posttransplant period from 54% (aHR 0.46) in normal-BMI to 32% (aHR 0.68) for morbidly obese patients. Relative benefits were largest for normal-weight candidates who received live-donor transplants (aHR 0.31).
conclusionsHeart failure risk improves in obese patients in the long term after kidney transplant, but not as much as for nonobese patients. There is need for close monitoring and for new strategies to reduce HF risk in obese patients before and after transplant.
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