Evidence map›Paper›PMID 19958132›Full record

Trial reportJournal of alternative and complementary medicine (New York, N.Y.)2009

Electrodermal measures of Jing-Well points and their clinical relevance in endometriosis-related chronic pelvic pain.

Andrew C Ahn, Rosa Schnyer, Lisa Conboy, Marc R Laufer, Peter M Wayne

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of alternative and complementary medicine (New York, N.Y.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Acupuncture for pain in endometriosis.The Cochrane database of systematic reviews · 2011
    Pooled it
  4. Reliability of AcuGraph system for measuring skin conductance at acupoints.Acupuncture in medicine : journal of the British Medical Acupuncture Society · 2011
    Trial
  5. The Science of Tai Chi andJournal of integrative and complementary medicine · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Acupoints Initiate the Healing Process.Medical acupuncture · 2014
    Review
  15. Acupuncture for Pediatric Pain.Children (Basel, Switzerland) · 2014
    Review
  16. Article
  17. Article
  18. Neural acupuncture unit: a new concept for interpreting effects and mechanisms of acupuncture.Evidence-based complementary and alternative medicine : eCAM · 2012
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Andrew C AhnDivision for Research and Education in Complementary and Integrative Medical Therapies, Harvard Medical School, 401 Park Drive Suite 22A-West, Boston, MA 02215, USA. aahn@hms.harvard.edu
Rosa Schnyer
Lisa Conboy
Marc R Laufer
Peter M Wayne
Harvard University · USNew England School of Acupuncture · USThe University of Texas at Austin · US

Funding

NESA Acupuncture Research CollaborativeU19AT002022 · NCCIH · NEW ENGLAND SCHOOL OF ACUPUNCTURE · PI WAYNE, PETER MICHAEL · 2003 to 2009
$4.0M
Mentoring and Research in Placebo Studies, Asian Medicine, and CAMK24AT004095 · NCCIH · HARVARD MEDICAL SCHOOL · PI KAPTCHUK, TED · 2007 to 2016
$1.4M
Biophysics of Acupuncture:Electrical Properties of Loose CTK23AT003238 · NCCIH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI AHN, ANDREW C · 2005 to 2009
$650k
NCCIH NIH HHS 5U19 AT 002022NCCIH NIH HHS K23 AT003238NCCIH NIH HHS K23-AT 003238NCCIH NIH HHS K24-AT 004095
6 · The paper itself

Abstract

objectivesTo determine whether electrodermal measures at Jing-Well acupuncture points, "indicator" points located at the tips of fingers and toes are associated with clinical measures in adolescent women with chronic pelvic pain.

designThe design of this study was a randomized sham-controlled trial. Analyses of electrodermal measures were based on longitudinal, multivariable analyses using generalized estimating equations. SUBJECTS AND

settingThe subjects were 14 young women (ages 14-22) with laparoscopically diagnosed endometriosis and chronic pelvic pain. Subjects were randomized to sham acupuncture or Japanese-style active acupuncture. Sixteen (16) treatments were administered over 8 weeks. OUTCOME MEASURES: Using a Hibiki-7 device, electrodermal impedance measures were obtained at all 24 Jing-Well points for each treatment visit. From these readings, measures of "imbalance" were determined by calculating statistical dispersion (statistical deviation and Gini coefficient) and level of asymmetry (left-right, top-bottom, and yin-yang). Clinical outcome measures were obtained at baseline, week 4, and week 8 and included level of pelvic pain, Endometriosis Health Profile, Pediatric Quality of Life, perceived stress, and inflammatory cytokine levels (interleukin-6 and tumor necrosis factor-alpha).

resultsParticipants designated to the acupuncture group had, on average, a substantial decrease in statistical dispersion and asymmetry of Hibiki-7 values over the course of treatment compared to the sham group. Electrodermal asymmetry variables, specifically either yin-yang or left-right measure, were significantly associated with pelvic pain, Endometriosis Health Profile, Pediatric Quality of Life, and Perceived Stress even after adjusting for treatment designation. No associations between electrodermal balance measures and inflammatory cytokines were found.

conclusionsElectrodermal measures may be significantly associated with clinical outcome and acupuncture treatments in adolescent women with chronic pelvic pain.

Indexed as

Acupuncture PointsAcupuncture TherapyGalvanic Skin ResponseAdolescentAnalysis of VarianceChronic DiseaseEndometriosisFemaleHumansPain MeasurementPelvic PainPlacebosQuality of LifeStress, PsychologicalTreatment OutcomeYoung AdultPlacebos

Identifiers

PMID19958132
PMCPMC2876713
OpenAlexW2012884438

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.