Tumorigenicity of human induced pluripotent stem cells depends on the balance of gene expression between p21 and p53.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed.

1. Novel cell sources for bone regeneration.MedComm · 2021
   Review
2. CDKN2B upregulation prevents teratoma formation in multipotent fibromodulin-reprogrammed cells.The Journal of clinical investigation · 2019
   Article
3. [Research progress in tumorigenicity of human induced pluripotent stem cells].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2015
   Article
4. Stem cell-based approach for the treatment of Parkinson's disease.Medical journal of the Islamic Republic of Iran · 2015
   Review
5. SOX9 accelerates ESC differentiation to three germ layer lineages by repressing SOX2 expression through P21 (WAF1/CIP1).Development (Cambridge, England) · 2014
   Article
6. Aggregation of Human Eyelid Adipose-derived Stem Cells by Human Body Fluids.Development & reproduction · 2012
   Article
7. Embryonic template-based generation and purification of pluripotent stem cell-derived cardiomyocytes for heart repair.Journal of cardiovascular translational research · 2012
   Review
8. The tumorigenicity of human embryonic and induced pluripotent stem cells.Nature reviews. Cancer · 2011
   Review

Corrections and comments

• Comment on
  Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells.2010

Authors and funding

3 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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