Evidence map›Paper›PMID 19955525›Full record

ArticleThe New England journal of medicine2009

Forecasting the effects of obesity and smoking on U.S. life expectancy.

Susan T Stewart, David M Cutler, Allison B Rosen

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in The New England journal of medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01800591 (UPHS Weight Loss Study), which is not on this map. Cited by 184 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
184citing papers in PubMed, 4 pooled it
58.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01800591 nacompletednot on this mapstarted 2013, after this paper: background citation

UPHS Weight Loss Study: Evaluating Methods to Use Health Benefits Design to Encourage Employee Weight Loss

TypeinterventionalSponsorUniversity of PennsylvaniaRan2013 to 2015Enrolled201ConditionsObesityArmsFinancial incentive
3 · Its place in the literature

Who cites it

184 citing papers in PubMed, 4 syntheses or guidelines pooled it, 473 citations in OpenAlex.

  1. Pooled it
  2. A developmental cascade perspective of paediatric obesity: A systematic review of preventive interventions from infancy through late adolescence.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2020
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  5. Patient-provided e-support in reduced intensity obesity treatment: The INSPIRE randomized controlled trial.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2020
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124 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Susan T StewartHarvard University Interfaculty Program for Health Systems Improvement, Boston, MA, USA. sstewart@nber.org
David M Cutler
Allison B Rosen
Harvard University · USNational Bureau of Economic Research · USUniversity of Michigan–Ann Arbor · US

Funding

Understanding and Improving Healthcare Decision-Making and Outcomes for People Living with Alzheimer's Disease and Related DementiasP01AG005842 · NIA · NATIONAL BUREAU OF ECONOMIC RESEARCH · PI JOSEPH J DOYLE · 1986 to 2026
$56.5M
NBER Center for Aging and Health Research-Post COVID-19 Experiences Among Adults with ADRDP30AG012810 · NIA · NATIONAL BUREAU OF ECONOMIC RESEARCH · PI DAVID M CUTLER · 1999 to 2026
$24.6M
Expanding the National Health AccountsP01AG031098 · NIA · NATIONAL BUREAU OF ECONOMIC RESEARCH · PI CUTLER, DAVID M · 2009 to 2013
$9.2M
NIA NIH HHS P01 AG005842NIA NIH HHS P01AG005842NIA NIH HHS P01 AG031098NIA NIH HHS P01AG031098NIA NIH HHS P30 AG012810NIA NIH HHS P30AG012810
6 · The paper itself

Abstract

backgroundAlthough increases in obesity over the past 30 years have adversely affected the health of the U.S. population, there have been concomitant improvements in health because of reductions in smoking. Having a better understanding of the joint effects of these trends on longevity and quality of life will facilitate more efficient targeting of health care resources.

methodsFor each year from 2005 through 2020, we forecasted life expectancy and quality-adjusted life expectancy for a representative 18-year-old, assuming a continuation of past trends in smoking (based on data from the National Health Interview Survey for 1978 through 1979, 1990 through 1991, 1999 through 2001, and 2004 through 2006) and past trends in body-mass index (BMI) (based on data from the National Health and Nutrition Examination Survey for 1971 through 1975, 1988 through 1994, 1999 through 2002, and 2003 through 2006). The 2003 Medical Expenditure Panel Survey was used to examine the effects of smoking and BMI on health-related quality of life.

resultsThe negative effects of increasing BMI overwhelmed the positive effects of declines in smoking in multiple scenarios. In the base case, increases in the remaining life expectancy of a typical 18-year-old are held back by 0.71 years or 0.91 quality-adjusted years between 2005 and 2020. If all U.S. adults became nonsmokers of normal weight by 2020, we forecast that the life expectancy of an 18-year-old would increase by 3.76 life-years or 5.16 quality-adjusted years.

conclusionsIf past obesity trends continue unchecked, the negative effects on the health of the U.S. population will increasingly outweigh the positive effects gained from declining smoking rates. Failure to address continued increases in obesity could result in an erosion of the pattern of steady gains in health observed since early in the 20th century.

Indexed as

AdolescentAdultAgedBody Mass IndexForecastingHumansLife ExpectancyMiddle AgedObesityQuality-Adjusted Life YearsRiskSmokingSmoking CessationUnited StatesYoung Adult

Identifiers

PMID19955525
PMCPMC4394736
OpenAlexW2108556721

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.