ArticleEuropean journal of human genetics : EJHG2010
Non-invasive prenatal testing: ethical issues explored.
Article in European journal of human genetics : EJHG, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.
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Who cites it
60 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Facilitating informed choice about non-invasive prenatal testing (NIPT): a systematic review and qualitative meta-synthesis of women's experiences.BMC pregnancy and childbirth · 2019Pooled it
- Access alone does not define equity in reproductive genetics.European journal of human genetics : EJHG · 2026Article
- Facing suffering honestly: On severity, utility, and the public good in reproductive genetic carrier screening.European journal of human genetics : EJHG · 2026Article
- Genome-Wide Prenatal cfDNA Screening and the Obstetric Incidentalome: Maternal Cancer, Placental Mosaicism, and Pregnancy Risk.International journal of women's health · 2026Review
- Awareness of down syndrome screening among educated Muslim women is associated with a favorable attitude toward testing.BMC women's health · 2024Article
- Preconception education program for non-invasive prenatal testing focused on interest in genetics among female university students in Japan: a quasi-experimental study comparing pre-intervention, post-intervention, and three-month follow-up results.Archives of public health = Archives belges de sante publique · 2023Article
- Biases in bioethics: a narrative review.BMC medical ethics · 2023Review
- Expanded Non-invasive Prenatal Testing (NIPT) : Can the Child's Right to an Open Future Help Set the Scope?Journal of bioethical inquiry · 2023Article
- Implementing Expanded Prenatal Genetic Testing: Should Parents Have Access to Any and All Fetal Genetic Information?The American journal of bioethics : AJOB · 2022Article
- Non-invasive prenatal paternity testing by analysis of Y-chromosome mini-STR haplotype using next-generation sequencing.PloS one · 2022Article
- Decision-making for prenatal genetic screening: how will pregnant women navigate a growing number of aneuploidy and carrier screening options?BMC pregnancy and childbirth · 2021Article
- [France and Great-Britain at the age of genomic medicine: new ethical challenges in reproductive medicine].Medecine sciences : M/S · 2019Article
- Improving women's knowledge about prenatal screening in the era of non-invasive prenatal testing for Down syndrome - development and acceptability of a low literacy decision aid.BMC pregnancy and childbirth · 2018Article
- Limits to the scope of non-invasive prenatal testing (NIPT): an analysis of the international ethical framework for prenatal screening and an interview study with Dutch professionals.BMC pregnancy and childbirth · 2018Article
- Medical genetics in developing countries in the Asia-Pacific region: challenges and opportunities.Genetics in medicine : official journal of the American College of Medical Genetics · 2018Review
- Patients' Knowledge of Prenatal Screening for Trisomy 21.Journal of genetic counseling · 2018Article
- Implementing non-invasive prenatal testing for aneuploidy in a national healthcare system: global challenges and national solutions.BMC health services research · 2017Article
- Knowledge and Attitudes Regarding Non-Invasive Prenatal Testing (NIPT) and Preferences for Risk Information among High School Students in Sweden.Journal of genetic counseling · 2017Article
- Detection of trisomies 13, 18 and 21 using non-invasive prenatal testing.Experimental and therapeutic medicine · 2017Article
- Development and evaluation of training resources to prepare health professionals for counselling pregnant women about non-invasive prenatal testing for Down syndrome: a mixed methods study.BMC pregnancy and childbirth · 2017Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper explores the ethical implications of introducing non-invasive prenatal diagnostic tests (NIPD tests) in prenatal screening for foetal abnormalities. NIPD tests are easy and safe and can be performed early in pregnancy. Precisely because of these features, it is feared that informed consent may become more difficult, that both testing and selective abortion will become 'normalized', and that there will be a trend towards accepting testing for minor abnormalities and non-medical traits as well. In our view, however, the real moral challenge of NIPD testing consists in the possibility of linking up a technique with these features (easy, safe and early) with new genomic technologies that allow prenatal diagnostic testing for a much broader range of abnormalities than is the case in current procedures. An increase in uptake and more selective abortions need not in itself be taken to signal a thoughtless acceptance of these procedures. However, combining this with considerably enlarging the scope of NIPD testing will indeed make informed consent more difficult and challenge the notion of prenatal screening as serving reproductive autonomy. If broad NIPD testing includes later-onset diseases, the 'right not to know' of the future child will become a new issue in the debate about prenatal screening. With regard to the controversial issue of selective abortion, it may make a morally relevant difference that after NIPD testing, abortion can be done early. A lower moral status may be attributed to the foetus at that moment, given the dominant opinion that the moral status of the foetus progressively increases with its development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.