Evidence map›Paper›PMID 19950260›Full record

ArticleArthritis and rheumatism2009

Increased tibiofemoral cartilage contact deformation in patients with anterior cruciate ligament deficiency.

Samuel K Van de Velde, Jeffrey T Bingham, Ali Hosseini, Michal Kozanek, Louis E DeFrate, Thomas J Gill, Guoan Li

Abstract read
In one paragraph

Article in Arthritis and rheumatism, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Longitudinal analysis of tibiofemoral cartilage contact area and position in ACL reconstructed patients.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2018
    Trial
  4. Trial
  5. Article
  6. Comparison of Dynamic Knee Contact Mechanics with TAnnals of biomedical engineering · 2023
    Article
  7. Article
  8. Review
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Article
  14. A longitudinal tear in the medial meniscal body decreased the in situ meniscus force under an axial load.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2020
    Article
  15. Effect of Different Knee Braces in ACL-Deficient Patients.Frontiers in bioengineering and biotechnology · 2020
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Samuel K Van de VeldeMassachusetts General Hospital/Harvard Medical School, Boston, Massachusetts 02114, USA.
Jeffrey T Bingham
Ali Hosseini
Michal Kozanek
Louis E DeFrate
Thomas J Gill
Guoan Li

Funding

In vivo ACL Reconstruction BiomechanicsR01AR055612 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI LI, GUOAN · 2008 to 2012
$1.9M
In Vivo PCL BiomechanicsR01AR052408 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI LI, GUOAN · 2005 to 2007
$1.1M
In-Vivo Ligamentous Tension of the KneeR21AR051078 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI LI, GUOAN · 2006 to 2007
$418k
NIAMS NIH HHS R01 AR052408NIAMS NIH HHS R01-AR-052408-02NIAMS NIH HHS R01 AR055612NIAMS NIH HHS R21 AR051078NIAMS NIH HHS R21-AR-051078-01
6 · The paper itself

Abstract

objectiveTo investigate the in vivo cartilage contact biomechanics of the tibiofemoral joint following anterior cruciate ligament (ACL) injury.

methodsEight patients with an isolated ACL injury in 1 knee, with the contralateral side intact, participated in the study. Both knees were imaged using a specific magnetic resonance sequence to create 3-dimensional models of knee bone and cartilage. Next, each patient performed a lunge motion from 0 degrees to 90 degrees of flexion as images were recorded with a dual fluoroscopic system. The three-dimensional knee models and fluoroscopic images were used to reproduce the in vivo knee position at each flexion angle. With this series of knee models, the location of the tibiofemoral cartilage contact, size of the contact area, cartilage thickness at the contact area, and magnitude of the cartilage contact deformation were compared between intact and ACL-deficient knees.

resultsRupture of the ACL changed the cartilage contact biomechanics between 0 degrees and 60 degrees of flexion in the medial compartment of the knee. Compared with the contralateral knee, the location of peak cartilage contact deformation on the tibial plateaus was more posterior and lateral, the contact area was smaller, the average cartilage thickness at the tibial cartilage contact area was thinner, and the resultant magnitude of cartilage contact deformation was increased. Similar changes were observed in the lateral compartment, with increased cartilage contact deformation from 0 degrees to 30 degrees of knee flexion in the presence of ACL deficiency.

conclusionACL deficiency alters the in vivo cartilage contact biomechanics by shifting the contact location to smaller regions of thinner cartilage and by increasing the magnitude of the cartilage contact deformation.

Indexed as

AdultAnterior Cruciate LigamentAnterior Cruciate Ligament InjuriesBiomechanical PhenomenaExercise TestFemaleFemurFluoroscopyHumansKnee InjuriesKnee JointMagnetic Resonance ImagingMaleTibiaWeight-BearingYoung Adult

Identifiers

PMID19950260
PMCPMC2914513

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.