ArticleClinical and experimental medicine2010
Comparison of tuberculin skin test and QuantiFERON-TB gold in tube test in patients with chronic inflammatory diseases living in a tuberculosis endemic population.
Article in Clinical and experimental medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Guideline
- Pooled it
- Interferon-gamma release assay for the diagnosis of latent tuberculosis infection: A latent-class analysis.PloS one · 2017Article
- IFN-γ release assays in the diagnosis of latent tuberculosis infection among immunocompromised adults.American journal of respiratory and critical care medicine · 2013Review
- Negative effect of immunosuppressive therapy in the performance of the QuantiFERON gold in-tube test in patients with immune-mediated inflammatory diseases.Clinical and experimental medicine · 2013Article
- Interferon-Gamma Release Assays versus Tuberculin Skin Testing for the Diagnosis of Latent Tuberculosis Infection: An Overview of the Evidence.Pulmonary medicine · 2013Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We aimed to compare tuberculin skin test (TST) and QuantiFERON-TB gold in tube (QFT-IT) in patients with chronic inflammatory diseases living in a population where tuberculosis is endemic and BCG vaccination is routine. Twenty-five patients with rheumatoid arthritis (RA), 16 patients with spondilarthropathy (SpA) and 7 healthy volunteers were recruited in the study. Blood samples were collected for QFT-IT test followed by TST. TST was considered to be positive with an enduration of 5 mm and over in patients with RA and SpA. The cutoff point for TST for the healthy control (HC) was 10 mm. Median TST result of patients who were using immunosuppressive drugs was significantly lower than that of patients who were not [5 (14.5), 13.5 (9.5), respectively, P = 0.04]. Poor agreement between TST and QFT-IT was seen in patients with RA (kappa = 0.141) and in patients with SpA (kappa = 0.190). We found poor concordance between QFT-IT and TST in patients with chronic inflammatory diseases, and TST response was suppressed in patients treated with immunosuppressive drugs.
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