ArticleJournal of Korean medical science2009
Differential immunohistological features of inflammatory myopathies and dysferlinopathy.
Article in Journal of Korean medical science, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 51 citations in OpenAlex.
- Pilot investigations into the mechanistic basis for adverse effects of glucocorticoids in dysferlinopathy.Skeletal muscle · 2024Article
- Expression of CD163 and major histocompatibility complex class I as diagnostic markers for idiopathic inflammatory myopathies.Arthritis research & therapy · 2024Article
- Immunohistochemical expression in idiopathic inflammatory myopathies at a single center in Vietnam.Journal of pathology and translational medicine · 2024Article
- Expression of Inflammatory Markers in the Muscles of Patients with Idiopathic Inflammatory Myopathy According to the Presence of Interstitial Lung Disease.Journal of clinical medicine · 2022Article
- The inflammatory pathology of dysferlinopathy is distinct from calpainopathy, Becker muscular dystrophy, and inflammatory myopathies.Acta neuropathologica communications · 2022Article
- A case of dermatomyositis in a patient with central core disease: unusual association with autoimmunity and genetic muscle disease.Pediatric rheumatology online journal · 2021Article
- A Patient With Late-onset Limb-girdle Muscular Dystrophy Type 2B Mimicking Dermatomyositis: A Case Report and Review.Journal of rheumatic diseases · 2021Article
- The Role of Innate and Adaptive Immune Cells in Skeletal Muscle Regeneration.International journal of molecular sciences · 2021Review
- Immunobiology of Inherited Muscular Dystrophies.Comprehensive Physiology · 2018Review
- The Role of T Lymphocytes in Skeletal Muscle Repair From Traumatic and Contraction-Induced Injury.Frontiers in physiology · 2018Review
- Comparative immunoprofiling of polymyositis and dermatomyositis muscles.International journal of clinical and experimental pathology · 2018Article
- Increased Cumulative Incidence of Dermatomyositis in Ulcerative Colitis: a Nationwide Cohort Study.Scientific reports · 2016Article
- CD4+ cells, macrophages, MHC-I and C5b-9 involve the pathogenesis of dysferlinopathy.International journal of clinical and experimental pathology · 2015Article
- Skeletal Muscle Inflammation Following Repeated Bouts of Lengthening Contractions in Humans.Frontiers in physiology · 2015Article
- Vitamin D receptor agonists: suitable candidates as novel therapeutic options in autoimmune inflammatory myopathy.BioMed research international · 2014Review
- From innate to adaptive immune response in muscular dystrophies and skeletal muscle regeneration: the role of lymphocytes.BioMed research international · 2014Review
- 7-Tesla magnetic resonance imaging precisely and noninvasively reflects inflammation and remodeling of the skeletal muscle in a mouse model of antisynthetase syndrome.BioMed research international · 2014Article
- Eosinophils in hereditary and inflammatory myopathies.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2013Article
- Role of non-immune mechanisms of muscle damage in idiopathic inflammatory myopathies.Arthritis research & therapy · 2012Review
- Heterogeneous characteristics of Korean patients with dysferlinopathy.Journal of Korean medical science · 2012Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study was performed in order to characterize the types of the infiltrating cells, and the expression profiles of major histocompatibility complex (MHC) class I and membrane attack complex (MAC) in patients with inflammatory myopathies and dysferlinopathy. Immunohistochemical stains were performed using monoclonal antibodies against several inflammatory cell types, MHC class I, and MAC in muscles from inflammatory myopathies and dysferlinopathy. There was significant difference in the types of infiltrating cells between polymyositis (PM), dermatomyositis (DM), and dysferlinopathy, including significantly high CD4+/CD8+ T cell ratio and B/T cell ratio in DM. In dysferlinopathy, CD4+ T cells were the most abundant and the proportions of infiltrating cell types were similar to those of DM. MHC class I was expressed in muscle fibers of PM and DM regardless of the presence of inflammatory infiltrates. MAC was expressed in necrotic fibers and vessels of PM and DM. One patient with early stage DM had a MAC deposits on endomysial capillaries. In dysferlinopathy, MAC deposit was also observed on the sarcolemma of nonnecrotic fibers. The analysis of inflammatory cells, MHC class I expressions and MAC deposits may help to differentiate dysferlinopathy from idiopathic inflammatory myopathy.
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