Apoptosis: it's BAK to VDAC.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

13 citing papers in PubMed.

1. The PVAT-MAMs Axis in Atherosclerosis: A Hypothesis-Driven Cross-Scale Conceptual Framework.International journal of molecular sciences · 2026
   Review
2. Fto-dependent Vdac3 m6A Modification Regulates Neuronal Ferroptosis Induced by the Post-ICH Mass Effect and Transferrin.Neuroscience bulletin · 2025
   Article
3. VDAC in Retinal Health and Disease.Biomolecules · 2024
   Review
4. Autophagy restricts mitochondrial DNA damage-induced release of ENDOG (endonuclease G) to regulate genome stability.Autophagy · 2021
   Article
5. AREL1 E3 ubiquitin ligase inhibits TNF-induced necroptosis via the ubiquitination of MTX2.Experimental and therapeutic medicine · 2021
   Article
6. Diabetes induces dysregulation of microRNAs associated with survival, proliferation and self-renewal in cardiac progenitor cells.Diabetologia · 2021
   Article
7. Dysfunction in the mitochondrial Fe-S assembly machinery leads to formation of the chemoresistant truncated VDAC1 isoform without HIF-1α activation.PloS one · 2018
   Article
8. VDAC2-specific cellular functions and the underlying structure.Biochimica et biophysica acta · 2016
   Review
9. Motifs of VDAC2 required for mitochondrial Bak import and tBid-induced apoptosis.Proceedings of the National Academy of Sciences of the United States of America · 2015
   Article
10. PUMA, a critical mediator of cell death--one decade on from its discovery.Cellular & molecular biology letters · 2012
    Review
11. Voltage-dependent-anion-channels (VDACs) in Arabidopsis have a dual localization in the cell but show a distinct role in mitochondria.Plant molecular biology · 2012
    Article
12. The structural biology of β-barrel membrane proteins: a summary of recent reports.Current opinion in structural biology · 2011
    Review
13. Down regulation of Tim50 in Trypanosoma brucei increases tolerance to oxidative stress.Molecular and biochemical parasitology
    Article

Corrections and comments

• Comment on
  VDAC2 is required for truncated BID-induced mitochondrial apoptosis by recruiting BAK to the mitochondria.2009

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as