Evidence map›Paper›PMID 19949062›Full record

ArticleAntimicrobial agents and chemotherapy2010

Detection and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates in Canada: results from the Canadian Nosocomial Infection Surveillance Program, 1995-2006.

Heather J Adam, Lisa Louie, Christine Watt, Denise Gravel, Elizabeth Bryce, Mark Loeb, Anne Matlow, Allison McGeer, Michael R Mulvey, Andrew E Simor and 1 more

Abstract read
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In one paragraph

Article in Antimicrobial agents and chemotherapy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Pooled it
  5. Pooled it
  6. Article
  7. [Strategies on the prevention and treatment of surgical site infection and the resulting wound].Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns · 2021
    Article
  8. Article
  9. Review
  10. Characterization of methicillin-resistant Staphylococcus aureus isolates from patients with persistent or recurrent bacteremia.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2014
    Article
  11. Article
  12. Is it time to replace vancomycin in the treatment of methicillin-resistant Staphylococcus aureus infections?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2013
    Article
  13. Article
  14. Detection of Staphylococcus aureus with an intermediate profile to vancomycin (VISA) isolate from Santa Maria, RS.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2013
    Article
  15. Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Heather J AdamDepartment of Laboratory Medicine & Pathobiology, University of Toronto, and Hospital for Sick Children, Toronto, Ontario, Canada.
Lisa Louie
Christine Watt
Denise Gravel
Elizabeth Bryce
Mark Loeb
Anne Matlow
Allison McGeer
Michael R Mulvey
Andrew E Simor
Canadian Nosocomial Infection Surveillance Program

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe the epidemiology of heterogeneously resistant Staphylococcus aureus (hVISA) identified in Canadian hospitals between 1995 and 2006. hVISA isolates were confirmed by the population analysis profiling-area under the curve method. Only 25 hVISA isolates (1.3% of all isolates) were detected. hVISA isolates were more likely to have been health care associated (odds ratio [OR], 5.1; 95% confidence interval [CI], 1.9 to 14.2) and to have been recovered from patients hospitalized in central Canada (OR, 3.0; 95% CI, 1.2 to 7.4). There has been no evidence of vancomycin "MIC creep" in Canadian strains of methicillin (meticillin)-resistant S. aureus, and hVISA strains are currently uncommon.

Indexed as

Anti-Bacterial AgentsCanadaCross InfectionDrug Resistance, Multiple, BacterialMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsStaphylococcal InfectionsVancomycinVancomycin ResistanceAnti-Bacterial AgentsVancomycin

Identifiers

PMID19949062
PMCPMC2812162

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.