Evidence map›Paper›PMID 19949060›Full record

ArticleAntimicrobial agents and chemotherapy2010

Atorvastatin as a potential antimalarial drug: in vitro synergy in combinational therapy with dihydroartemisinin.

Hélène Savini, Jean Baptiste Souraud, Sébastien Briolant, Eric Baret, Rémy Amalvict, Christophe Rogier, Bruno Pradines

Open access · greenAbstract readLetter
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Antiplasmodial, Trypanocidal, and GenotoxicityPharmaceuticals (Basel, Switzerland) · 2023
    Article
  3. Primaquine derivatives: Modifications of the terminal amino group.European journal of medicinal chemistry · 2019
    Review
  4. Atorvastatin: In-Vivo Synergy with Metronidazole as Anti-The Korean journal of parasitology · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hélène Savini
Jean Baptiste Souraud
Sébastien Briolant
Eric Baret
Rémy Amalvict
Christophe Rogier
Bruno Pradines
Institut de Médecine Tropicale du Service de Santé des Armées · FRHôpital d'Instruction des Armées Sainte-Anne · FRHôpital Laveran · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntimalarialsArtemisininsAtorvastatinDrug CombinationsDrug SynergismHeptanoic AcidsParasitic Sensitivity TestsPlasmodium falciparumPyrrolesAntimalarialsArtemisininsartenimolAtorvastatinDrug CombinationsHeptanoic AcidsPyrroles

Identifiers

PMID19949060
PMCPMC2812141
OpenAlexW2029477937

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.