ArticleApplied and environmental microbiology2010
Molecular detection of viable bacterial pathogens in water by ratiometric pre-rRNA analysis.
Article in Applied and environmental microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Probing Dermal Immunity to Mycobacteria through a Controlled Human Infection Model.ImmunoHorizons · 2024Trial
- Spinal infections.Frontiers in neuroscience · 2026Review
- Novel molecular assessment method using precursor ribosomal RNA to rapidly quantify hard-to-monitor pathogens in aqueous suspensions: application to ultraviolet disinfection ofJournal of water and health · 2025Article
- Molecular detection of pre-ribosomal RNAs of Mycobacterium bovis bacille Calmette-Guérin and Mycobacterium tuberculosis to enhance pre-clinical tuberculosis drug and vaccine development.Diagnostic microbiology and infectious disease · 2024Article
- Laboratory diagnostics for primary spinal infections in pediatric and adult populations: a narrative review.North American Spine Society journal · 2023Article
- Precise in-field molecular diagnostics of crop diseases by smartphone-based mutation-resolved pathogenic RNA analysis.Nature communications · 2023Article
- A rapid and reliable method for the determination ofFrontiers in microbiology · 2023Article
- Steady-State Pre-rRNA Analysis to Investigate the Functional Microbiome.Current protocols · 2021Article
- Mycobacterium tuberculosis precursor rRNA as a measure of treatment-shortening activity of drugs and regimens.Nature communications · 2021Article
- Evaluation of a pan-Leishmania SL RNA qPCR assay for parasite detection in laboratory-reared and field-collected sand flies and reservoir hosts.Parasites & vectors · 2020Article
- RNA-based qPCR as a tool to quantify and to characterize dual-species biofilms.Scientific reports · 2019Article
- Methods for quantification of growth and productivity in anaerobic microbiology and biotechnology.Folia microbiologica · 2019Review
- Molecular viability testing of viable but non-culturable bacteria induced by antibiotic exposure.Microbial biotechnology · 2018Article
- Differences in Temperature and Water Chemistry Shape Distinct Diversity Patterns in Thermophilic Microbial Communities.Applied and environmental microbiology · 2017Article
- Schrödinger's microbes: Tools for distinguishing the living from the dead in microbial ecosystems.Microbiome · 2017Review
- Molecular Viability Testing of UV-Inactivated Bacteria.Applied and environmental microbiology · 2017Article
- In Situ Anabolic Activity of Periodontal Pathogens Porphyromonas gingivalis and Filifactor alocis in Chronic Periodontitis.Scientific reports · 2016Article
- Abundance and Distribution of Enteric Bacteria and Viruses in Coastal and Estuarine Sediments-a Review.Frontiers in microbiology · 2016Review
- Dead or alive: molecular assessment of microbial viability.Applied and environmental microbiology · 2014Review
- Biosynthetic enhancement of the detection of bacteria by the polymerase chain reaction.PloS one · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ratiometric pre-rRNA analysis (RPA) detects the replenishment of rRNA precursors that occurs rapidly upon nutritional stimulation of bacterial cells. In contrast to DNA detection by PCR, RPA distinguishes viable from inactivated bacteria. It exhibits promise as a molecular viability test for pathogens in water and other environmental samples.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.