Trial reportBMJ (Clinical research ed.)2009
Are people with negative diabetes screening tests falsely reassured? Parallel group cohort study embedded in the ADDITION (Cambridge) randomised controlled trial.
Trial report in BMJ (Clinical research ed.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Measurement of Perceived Risk of Developing Diabetes Mellitus: A Systematic Literature Review.Journal of general internal medicine · 2023Pooled it
- Atherosclerosis screening by noninvasive imaging for cardiovascular prevention: a systematic review.Journal of general internal medicine · 2012Pooled it
- Long-term effect of population screening for diabetes on cardiovascular morbidity, self-rated health, and health behavior.Annals of family medicine · 2015Trial
- Using web-based familial risk information for diabetes prevention: a randomized controlled trial.BMC public health · 2013Trial
- Screening for type 2 diabetes and population mortality over 10 years (ADDITION-Cambridge): a cluster-randomised controlled trial.Lancet (London, England) · 2012Trial
- Effect of screening for Type 2 diabetes on population-level self-rated health outcomes and measures of cardiovascular risk: 13-year follow-up of the Ely cohort.Diabetic medicine : a journal of the British Diabetic Association · 2012Trial
- ExploringBiomedical optics express · 2024Article
- Use of smartphone application versus written titration charts for basal insulin titration in adults with type 2 diabetes and suboptimal glycaemic control (My Dose Coach): multicentre, open-label, parallel, randomised controlled trial.The Lancet regional health. Europe · 2023Article
- Screening for Diabetes and Prediabetes.Endocrinology and metabolism clinics of North America · 2021Review
- Psychological impact of providing women with personalised 10-year breast cancer risk estimates.British journal of cancer · 2018Article
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- Impact of a diabetes screening program on a rural Chinese population: a 3-year follow-up study.BMC public health · 2015Article
- Motivation and experiences of self-testers regarding tests for cardiovascular risk factors.Health expectations : an international journal of public participation in health care and health policy · 2014Article
- Detecting type 2 diabetes and prediabetes among asymptomatic adults in the United States: modeling American Diabetes Association versus US Preventive Services Task Force diabetes screening guidelines.Population health metrics · 2014Article
- Estimating the potential population impact of stepwise screening strategies for identifying and treating individuals at high risk of Type 2 diabetes: a modelling study.Diabetic medicine : a journal of the British Diabetic Association · 2012Article
- Screening for diabetes: hope and despair.Diabetologia · 2012Article
- Impact and cost of a 2-week community-based screening and awareness program for diabetes and cardiovascular risk factors in a Swiss canton.Diabetes, metabolic syndrome and obesity : targets and therapy · 2011Article
- TRAF4 functions as an intermediate of GITR-induced NF-kappaB activation.Cellular and molecular life sciences : CMLS · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 6 institutions in 2 countries.
Funding
Abstract
objectiveTo assess whether receiving a negative test result at primary care based stepwise diabetes screening results in false reassurance.
designParallel group cohort study embedded in a randomised controlled trial.
setting15 practices (10 screening, 5 control) in the ADDITION (Cambridge) trial.
participants5334 adults (aged 40-69) in the top quarter for risk of having undiagnosed type 2 diabetes (964 controls and 4370 screening attenders).
main outcome measuresPerceived personal and comparative risk of diabetes, intentions for behavioural change, and self rated health measured after an initial random blood glucose test and at 3-6 and 12-15 months later (equivalent time points for controls).
resultsA linear mixed effects model with control for clustering by practice found no significant differences between controls and people who screened negative for diabetes in perceived personal risk, behavioural intentions, or self rated health after the first appointment or at 3-6 months or 12-15 months later. After the initial test, people who screened negative reported significantly (but slightly) lower perceived comparative risk (mean difference -0.16, 95% confidence interval -0.30 to -0.02; P=0.04) than the control group at the equivalent time point; no differences were evident at 3-6 and 12-15 months.
conclusionsA negative test result at diabetes screening does not seem to promote false reassurance, whether this is expressed as lower perceived risk, lower intentions for health related behavioural change, or higher self rated health. Implementing a widespread programme of primary care based stepwise screening for type 2 diabetes is unlikely to cause an adverse shift in the population distribution of plasma glucose and cardiovascular risk resulting from an increase in unhealthy behaviours arising from false reassurance among people who screen negative. Trial registration Current controlled trials ISRCTN99175498.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.