Evidence map›Paper›PMID 19948623›Full record

Trial reportPediatrics2009

Adherence feedback to improve asthma outcomes among inner-city children: a randomized trial.

Michiko Otsuki, Michelle N Eakin, Cynthia S Rand, Arlene M Butz, Van Doren Hsu, Ilene H Zuckerman, Jean Ogborn, Andrew Bilderback, Kristin A Riekert

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Pediatrics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 11 syntheses or guidelines pooled it.

  1. Home-based educational interventions for children with asthma.The Cochrane database of systematic reviews · 2025
    Pooled it
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  4. Interventions to improve adherence to inhaled steroids for asthma.The Cochrane database of systematic reviews · 2017
    Pooled it
  5. Technology-mediated interventions for enhancing medication adherence.Journal of the American Medical Informatics Association : JAMIA · 2015
    Pooled it
  6. Interventions for enhancing medication adherence.The Cochrane database of systematic reviews · 2014
    Pooled it
  7. Pooled it
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  10. Interventions to increase medication adherence in African-American and Latino populations: a literature review.Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health · 2014
    Pooled it
  11. Home-based educational interventions for children with asthma.The Cochrane database of systematic reviews · 2011
    Pooled it
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  13. Controller adherence following hospital discharge in high risk children: A pilot randomized trial of text message reminders.The Journal of asthma : official journal of the Association for the Care of Asthma · 2019
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michiko OtsukiDepartment of Psychology, University of South Florida St Petersburg, St Petersburg, Florida, USA.
Michelle N Eakin
Cynthia S Rand
Arlene M Butz
Van Doren Hsu
Ilene H Zuckerman
Jean Ogborn
Andrew Bilderback
Kristin A Riekert

Funding

ADHERENCE INTERVENTION FOR MINORITY CHILDREN WITH ASTHMAR18HL063333 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI RAND, CYNTHIA S · 2000 to 2003
$1.5M
ADHERENCE INTERVENTION FOR MINORITY CHILDREN WITH ASTHMAR01HL063333 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI RAND, CYNTHIA S · 2001 to 2001
$601k
NHLBI NIH HHS HL063333NHLBI NIH HHS R01 HL063333NHLBI NIH HHS R18 HL063333
6 · The paper itself

Abstract

objectiveWe evaluated the longitudinal effects of home-based asthma education combined with medication adherence feedback (adherence monitoring with feedback [AMF]) and asthma education alone (asthma basic care [ABC]) on asthma outcomes, relative to a usual-care (UC) control group.

methodsA total of 250 inner-city children with asthma (mean age: 7 years; 62% male; 98% black) were recruited from a pediatric emergency department (ED). Health-outcome measures included caregiver-frequency of asthma symptoms, ED visits, hospitalizations, and courses of oral corticosteroids at baseline and 6-, 12-, and 18-month assessments. Adherence measures included caregiver-reported adherence to inhaled corticosteroid (ICS) therapy and pharmacy records of ICS refills. Multilevel modeling was used to examine the differential effects of AMF and ABC compared with UC.

resultsED visits decreased more rapidly for the AMF group than for the UC group, but no difference was found between the ABC and UC groups. The AMF intervention led to short-term improvements in ICS adherence during the active-intervention phase relative to UC, but this improvement decreased over time. Asthma symptoms and courses of corticosteroids decreased more rapidly for the ABC group than for the UC group. Hospitalization rates did not differ between either intervention group and the UC group. No differences were found between the ABC and AMF groups on any outcome.

conclusionsAsthma education led to improved adherence and decreased morbidity compared with UC. Home-based educational interventions may lead to modest short-term improvements in asthma outcomes among inner-city children. Adherence feedback did not improve outcomes over education alone.

Indexed as

FeedbackMedication AdherencePatient Education as TopicUrban PopulationAdministration, InhalationAdministration, OralAdrenal Cortex HormonesAmbulatory CareAnti-Asthmatic AgentsAsthmaBaltimoreChildChild, PreschoolCross-Sectional StudiesEmergency Service, HospitalFemaleAdrenal Cortex HormonesAnti-Asthmatic Agents

Identifiers

PMID19948623
PMCPMC5450495

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.