ReviewThe Journal of cell biology2009
Eukaryotic systems broaden the scope of synthetic biology.
Review in The Journal of cell biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Molecular structures guide the engineering of chromatin.Nucleic acids research · 2017Article
- Promoter Screening from Bacillus subtilis in Various Conditions Hunting for Synthetic Biology and Industrial Applications.PloS one · 2016Article
- Constructing de novo H2O2 signaling via induced protein proximity.ACS chemical biology · 2015Article
- Article
- Genetically encoded sender-receiver system in 3D mammalian cell culture.ACS synthetic biology · 2014Article
- Modular, rule-based modeling for the design of eukaryotic synthetic gene circuits.BMC systems biology · 2013Article
- Gene autoregulation via intronic microRNAs and its functions.BMC systems biology · 2012Article
- Engineering synthetic TAL effectors with orthogonal target sites.Nucleic acids research · 2012Article
- Synthetic memory circuits for tracking human cell fate.Genes & development · 2012Article
- Parts plus pipes: synthetic biology approaches to metabolic engineering.Metabolic engineering · 2012Review
- A sensitive switch for visualizing natural gene silencing in single cells.ACS synthetic biology · 2012Article
- Emerging biomedical applications of synthetic biology.Nature reviews. Genetics · 2011Review
- In silico feedback for in vivo regulation of a gene expression circuit.Nature biotechnology · 2011Article
- From DNA to targeted therapeutics: bringing synthetic biology to the clinic.Science translational medicine · 2011Review
- Synthetic reversal of epigenetic silencing.The Journal of biological chemistry · 2011Article
- Article
- Unraveling condition-dependent networks of transcription factors that control metabolic pathway activity in yeast.Molecular systems biology · 2010Article
- Rational design of modular circuits for gene transcription: A test of the bottom-up approach.Journal of biological engineering · 2010Article
- Cell biology beyond the cell.The Journal of cell biology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synthetic biology aims to engineer novel cellular functions by assembling well-characterized molecular parts (i.e., nucleic acids and proteins) into biological "devices" that exhibit predictable behavior. Recently, efforts in eukaryotic synthetic biology have sprung from foundational work in bacteria. Designing synthetic circuits to operate reliably in the context of differentiating and morphologically complex cells presents unique challenges and opportunities for progress in the field. This review surveys recent advances in eukaryotic synthetic biology and describes how synthetic systems can be linked to natural cellular processes in order to manipulate cell behavior and to foster new discoveries in cell biology research.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.