Optimization of allele-specific PCR using patient-specific HIV consensus sequences for primer design.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

1. Concordance between allele-specific PCR and ultra-deep pyrosequencing for the detection of HIV-1 non-nucleoside reverse transcriptase inhibitor resistance mutations.Journal of virological methods · 2014
   Trial
2. Low-frequency nevirapine (NVP)-resistant HIV-1 variants are not associated with failure of antiretroviral therapy in women without prior exposure to single-dose NVP.The Journal of infectious diseases · 2014
   Trial
3. Short-course Combivir after single-dose nevirapine reduces but does not eliminate the emergence of nevirapine resistance in women.Antiviral therapy · 2012
   Trial
4. Role of low-frequency HIV-1 variants in failure of nevirapine-containing antiviral therapy in women previously exposed to single-dose nevirapine.Proceedings of the National Academy of Sciences of the United States of America · 2011
   Trial
5. Future technologies for monitoring HIV drug resistance and cure.Current opinion in HIV and AIDS · 2017
   Review
6. Longitudinal Detection and Persistence of Minority Drug-Resistant Populations and Their Effect on Salvage Therapy.PloS one · 2015
   Article
7. HIV-1 drug resistance in the iPrEx preexposure prophylaxis trial.The Journal of infectious diseases · 2014
   Article
8. PAPNC, a novel method to calculate nucleotide diversity from large scale next generation sequencing data.Journal of virological methods · 2014
   Article
9. Simultaneous detection of major drug resistance mutations in the protease and reverse transcriptase genes for HIV-1 subtype C by use of a multiplex allele-specific assay.Journal of clinical microbiology · 2013
   Article
10. Clinical implications of HIV-1 minority variants.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2013
    Article
11. Highly-sensitive allele-specific PCR testing identifies a greater prevalence of transmitted HIV drug resistance in Japan.PloS one · 2013
    Article
12. Ultrasensitive allele-specific PCR reveals rare preexisting drug-resistant variants and a large replicating virus population in macaques infected with a simian immunodeficiency virus containing human immunodeficiency virus reverse transcriptase.Journal of virology · 2012
    Article
13. Highly sensitive and specific detection of rare variants in mixed viral populations from massively parallel sequence data.PLoS computational biology · 2012
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

13 authors at 8 institutions in 4 countries.

Funding

Abstract

Indexed as