ArticleBMC neurology2009
The burden of stroke and transient ischemic attack in Pakistan: a community-based prevalence study.
Article in BMC neurology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and incidence of transient ischaemic attack: a systematic review and meta-analysis.BMC neurology · 2026Pooled it
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- Building confident cohesive stroke response teams: Design, implementation and outcomes of a stroke code simulation training program for interprofessional teams in LMIC.eNeurologicalSci · 2026Article
- Burden of cardiovascular disease in Pakistan - insight from global burden of disease study 2019.BMC cardiovascular disorders · 2026Article
- Longitudinal trends in stroke risk factors and mortality over 20 years from a central stroke referral center in Pakistan using clinically digitized data.eNeurologicalSci · 2025Article
- Gender-Based Differences in Stroke Types and Risk Factors Among Young Adults: A Comparative Retrospective Analysis.Journal of clinical medicine · 2025Article
- Deep brain stimulation for post-stroke rehabilitation in Pakistan.Annals of medicine and surgery (2012) · 2024Review
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- Effects of Virtual Reality-Based Mirror Therapy on Upper Extremity Motor Function, Manual Performance and Gross Manual Dexterity Among Stroke Patients: A Meta-Analysis.International journal of exercise science · 2024Review
- Cost of Investigating Neurological Disease: Experience of a Tertiary Care Center in Karachi, Pakistan.Cureus · 2020Article
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- Article
- Spectrum of neurological disorders in neurology outpatients clinics in urban and rural Sindh, Pakistan: a cross sectional study.BMC neurology · 2019Article
- Neuroprotective effects of human bone marrow mesenchymal stem cells against cerebral ischemia are mediated in part by an anti-apoptotic mechanism.Neural regeneration research · 2019Article
- Association of Plasma Levels of Nitric Oxide Oxidative Metabolites with Acute Stroke in Patients Presenting to the Emergency Department of a Low-Middle Income Country.Emergency medicine international · 2019Article
- Article
- Screening of Asymptomatic Intracranial Arterial Stenosis among High Risk Subjects: A Pilot Study from Egypt.Journal of vascular and interventional neurology · 2018Article
- Pattern of neurological diseases in adult outpatient neurology clinics in tertiary care hospital.BMC research notes · 2017Observational
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe burden of cerebrovascular disease in developing countries is rising sharply. The prevalence of established risk factors of stroke is exceptionally high in Pakistan. However, there is limited data on the burden of stroke and transient ischemic attack (TIA) in South Asia. We report the first such study conducted in an urban slum of Karachi, Pakistan.
methodsIndividuals 35 years of age or older were invited for participation in this investigation through simple random sampling. A structured face-to-face interview was conducted using a pre-tested stroke symptom questionnaire in each participant to screen for past stroke or TIA followed by neurological examination of suspected cases. Anthropometric measurements and random blood glucose levels were recorded. Multivariable logistic regression was used to determine the association of vascular risk factors with prevalence of stroke.
resultsFive hundred and forty five individuals (49.4% females) participated in the study with a response rate of 90.8%. One hundred and four individuals (19.1%) were observed to have a prior stroke while TIA was found in 53 individuals (9.7%). Overall, 119 individuals (21.8% with 66.4% females) had stroke and/or TIA. Female gender, old age, raised random blood glucose level and use of chewable tobacco were significantly associated with the prevalence of cerebrovascular disease.
conclusionThis is the first study demonstrating an alarmingly high life-time prevalence of cerebrovascular disease in Pakistan. Individual and public health interventions in Pakistan to increase awareness about stroke, its prevention and therapy are warranted.
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