ReviewCellular and molecular life sciences : CMLS2010
Megasatellites: a new class of large tandem repeats discovered in the pathogenic yeast Candida glabrata.
Review in Cellular and molecular life sciences : CMLS, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
- Chromosome-level assemblies from diverse clades reveal limited structural and gene content variation in the genome of Candida glabrata.BMC biology · 2022Article
- Article
- Characterization of Awp14, A Novel Cluster III Adhesin Identified in a High Biofilm-FormingFrontiers in cellular and infection microbiology · 2021Article
- The Epithelial adhesin 1 tandem repeat region mediates protein display through multiple mechanisms.FEMS yeast research · 2020Article
- Adhesins inJournal of fungi (Basel, Switzerland) · 2018Review
- Generational distribution of a Candida glabrata population: Resilient old cells prevail, while younger cells dominate in the vulnerable host.PLoS pathogens · 2017Article
- Genome-wide replication landscape of Candida glabrata.BMC biology · 2015Article
- One small step for a yeast--microevolution within macrophages renders Candida glabrata hypervirulent due to a single point mutation.PLoS pathogens · 2014Article
- Deep conservation of human protein tandem repeats within the eukaryotes.Molecular biology and evolution · 2014Article
- Detection and characterization of megasatellites in orthologous and nonorthologous genes of 21 fungal genomes.Eukaryotic cell · 2013Article
- Adhesins in human fungal pathogens: glue with plenty of stick.Eukaryotic cell · 2013Review
- Balanced gene losses, duplications and intensive rearrangements led to an unusual regularly sized genome in Arbutus unedo chloroplasts.PloS one · 2013Article
- Heterogeneous expression of the virulence-related adhesin Epa1 between individual cells and strains of the pathogen Candida glabrata.Eukaryotic cell · 2012Article
- Candida glabrata Pwp7p and Aed1p are required for adherence to human endothelial cells.FEMS yeast research · 2011Article
- From Saccharomyces cerevisiae to Candida glabratain a few easy steps: important adaptations for an opportunistic pathogen.FEMS microbiology letters · 2011Review
- Dynamic evolution of megasatellites in yeasts.Nucleic acids research · 2010Article
- Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Megasatellites are DNA tandem arrays made of large motifs; they were discovered in the yeast Candida glabrata. They are widespread in this species (40 copies) but are not found in any other hemiascomycete so far, raising the intriguing question of their origin. They are found mainly in genes encoding cell wall products, suggesting that megasatellites were selected for a function linked to cell-cell adhesion or to pathogenicity. Their putative role in promoting genome rearrangements by interfering with DNA replication will also be discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.