ArticleMolecular plant2009
Targeted gene knockouts reveal overlapping functions of the five Physcomitrella patens FtsZ isoforms in chloroplast division, chloroplast shaping, cell patterning, plant development, and gravity sensing.
Article in Molecular plant, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 50 citations in OpenAlex.
- A surface morphology-based inference method for the cell wall elasticity profile in tip-growing cells.PLoS computational biology · 2026Article
- Differential GTP-dependent in-vitro polymerization of recombinant Physcomitrella FtsZ proteins.Scientific reports · 2025Article
- Evolution and Functional Differentiation of the C-terminal Motifs of FtsZs During Plant Evolution.Molecular biology and evolution · 2024Article
- What can hornworts teach us?Frontiers in plant science · 2023Review
- Autopolyploidization affects transcript patterns and gene targeting frequencies in Physcomitrella.Plant cell reports · 2022Article
- Loss of Plastid Developmental Genes Coincides With a Reversion to Monoplastidy in Hornworts.Frontiers in plant science · 2022Article
- The hornworts: morphology, evolution and development.The New phytologist · 2021Review
- A NanoFE simulation-based surrogate machine learning model to predict mechanical functionality of protein networks from live confocal imaging.Computational and structural biotechnology journal · 2020Article
- Cytological analysis and structural quantification of FtsZ1-2 and FtsZ2-1 network characteristics in Physcomitrella patens.Scientific reports · 2018Article
- F-Actin Mediated Focusing of Vesicles at the Cell Tip Is Essential for Polarized Growth.Plant physiology · 2018Article
- The Molecular Machinery of Chloroplast Division.Plant physiology · 2018Review
- Transcriptome analysis of Brachypodium during fungal pathogen infection reveals both shared and distinct defense responses with wheat.Scientific reports · 2017Article
- Article
- A hypergravity environment increases chloroplast size, photosynthesis, and plant growth in the moss Physcomitrella patens.Journal of plant research · 2017Article
- Review
- FtsZ-less prokaryotic cell division as well as FtsZ- and dynamin-less chloroplast and non-photosynthetic plastid division.Frontiers in plant science · 2014Review
- Mobility of photosynthetic proteins.Photosynthesis research · 2013Review
- Identification of two additional members of the tRNA isopentenyltransferase family in Physcomitrella patens.Plant molecular biology · 2013Article
- Analysis of the chloroplast proteome in arc mutants and identification of novel protein components associated with FtsZ2.Plant molecular biology · 2013Article
- Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chloroplasts and bacterial cells divide by binary fission. The key protein in this constriction division is FtsZ, a self-assembling GTPase similar to eukaryotic tubulin. In prokaryotes, FtsZ is almost always encoded by a single gene, whereas plants harbor several nuclear-encoded FtsZ homologs. In seed plants, these proteins group in two families and all are exclusively imported into plastids. In contrast, the basal land plant Physcomitrella patens, a moss, encodes a third FtsZ family with one member. This protein is dually targeted to the plastids and to the cytosol. Here, we report on the targeted gene disruption of all ftsZ genes in P. patens. Subsequent analysis of single and double knockout mutants revealed a complex interaction of the different FtsZ isoforms not only in plastid division, but also in chloroplast shaping, cell patterning, plant development, and gravity sensing. These results support the concept of a plastoskeleton and its functional integration into the cytoskeleton, at least in the moss P. patens.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.