Evidence map›Paper›PMID 19946137›Full record

ReviewMicrobiology and molecular biology reviews : MMBR2009

Working toward the future: insights into Francisella tularensis pathogenesis and vaccine development.

Roger D Pechous, Travis R McCarthy, Thomas C Zahrt

Abstract readReview
In one paragraph

Review in Microbiology and molecular biology reviews : MMBR, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Genetic Homogeneity ofPathogens (Basel, Switzerland) · 2024
    Article
  7. Article
  8. Article
  9. Breaking the cellular defense: the role of autophagy evasion inFrontiers in cellular and infection microbiology · 2024
    Article
  10. Article
  11. Cells · 2023
    Article
  12. Article
  13. Characterization of threeAccess microbiology · 2023
    Article
  14. Comparative evaluation of protective immunity againstFrontiers in cellular and infection microbiology · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Roger D PechousCenter for Biopreparedness and Infectious Disease, Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226-0509, USA.
Travis R McCarthy
Thomas C Zahrt

Funding

Vaccines and Therapies Against BotulismU54AI057153 · NIAID · UNIVERSITY OF CHICAGO · PI SHUMAN, HOWARD A · 2003 to 2013
$87.6M
NIAID NIH HHS 1-U54-AI-057153NIAID NIH HHS R01-AI-06344NIAID NIH HHS U54 AI057153
6 · The paper itself

Abstract

Francisella tularensis is a facultative intracellular gram-negative pathogen and the etiological agent of the zoonotic disease tularemia. Recent advances in the field of Francisella genetics have led to a rapid increase in both the generation and subsequent characterization of mutant strains exhibiting altered growth and/or virulence characteristics within various model systems of infection. In this review, we summarize the major properties of several Francisella species, including F. tularensis and F. novicida, and provide an up-to-date synopsis of the genes necessary for pathogenesis by these organisms and the determinants that are currently being targeted for vaccine development.

Indexed as

Francisella tularensisTularemiaAnimalsBacterial VaccinesGenes, BacterialHost-Pathogen InteractionsHumansVaccinationVirulenceVirulence FactorsBacterial VaccinesVirulence Factors

Identifiers

PMID19946137
PMCPMC2786580

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.