ArticleJournal of insect physiology2010
Modulation of motor behavior by dopamine and the D1-like dopamine receptor AmDOP2 in the honey bee.
Article in Journal of insect physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed.
- Article
- Tribolium castaneum with longer duration of tonic immobility have more variations corresponding to the human Parkinson's disease genomic region.Scientific reports · 2026Article
- Article
- Chronic Larval Exposure to Lambda-Cyhalothrin Alters Gene Expression in Both Larval and Adult Honey Bees (Insects · 2025Article
- Caste- and age-specific venom composition of biogenic amines and the influence of diet in honey bees.PloS one · 2025Article
- The role of dopamine in foraging decisions in social insects.Frontiers in insect science · 2025Review
- Effects of Artificial Sugar Supplementation on the Composition and Nutritional Potency of Honey fromInsects · 2024Article
- Invasive ant learning is not affected by seven potential neuroactive chemicals.Current zoology · 2024Article
- Gut microbiota from patients with Parkinson's disease causes motor deficits in honeybees.Frontiers in microbiology · 2024Article
- MicroRNA ame-let-7 targets Amdop2 to increase sucrose sensitivity in honey bees (Apis mellifera).Frontiers in zoology · 2023Article
- Low-nutrient diet inOpen biology · 2023Article
- Honey bee functional genomics using symbiont-mediated RNAi.Nature protocols · 2023Review
- Conceptual framework for the insect metamorphosis from larvae to pupae by transcriptomic profiling, a case study of Helicoverpa armigera (Lepidoptera: Noctuidae).BMC genomics · 2022Article
- Genes associated with hot defensive bee ball in the Japanese honeybee, Apis cerana japonica.BMC ecology and evolution · 2022Article
- Parasitoid wasp venom manipulates host innate behavior via subtype-specific dopamine receptor activation.The Journal of experimental biology · 2022Article
- Differential Expression of Three Dopamine Receptors in Varroa-Resistant Honey Bees.Journal of insect science (Online) · 2022Article
- Effects of aversive conditioning on expression of physiological stress in honey bees (Apis mellifera).Neurobiology of learning and memory · 2021Article
- Octopamine and dopamine mediate waggle dance following and information use in honeybees.Proceedings. Biological sciences · 2020Article
- Differential expression of acetylcholinesterase 1 in response to various stress factors in honey bee workers.Scientific reports · 2019Article
- Effects of sublethal doses of clothianidin and/or V. destructor on honey bee (Apis mellifera) self-grooming behavior and associated gene expression.Scientific reports · 2019Article
Corrections and comments
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3 authors.
Funding
Abstract
Determining the specific molecular pathways through which dopamine affects behavior has been complicated by the presence of multiple dopamine receptor subtypes that couple to different second messenger pathways. The observation of freely moving adult bees in an arena was used to investigate the role of dopamine signaling in regulating the behavior of the honey bee. Dopamine or the dopamine receptor antagonist flupenthixol was injected into the hemolymph of worker honey bees. Significant differences between treated and control bees were seen for all behaviors (walking, stopped, upside down, grooming, flying and fanning), and behavioral shifts were dependent on drug dosage and time after injection. To examine the role of dopamine signaling through a specific dopamine receptor in the brain, RNA interference was used to reduce expression levels of a D1-like receptor, AmDOP2. Injection of Amdop2 dsRNA into the mushroom bodies reduced the levels of Amdop2 mRNA and produced significant changes in the amount of time honey bees spent performing specific behaviors with reductions in time spent walking offset by increases in grooming or time spent stopped. Taken together these results establish that dopamine plays an important role in regulating motor behavior of the honey bee.
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