Evidence map›Paper›PMID 19944301›Full record

ArticleObstetrics and gynecology clinics of North America2009

Update and critique of natural remedies as antidepressant treatments.

David Mischoulon

Abstract read
In one paragraph

Article in Obstetrics and gynecology clinics of North America, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Postmenopausal Symptoms and Their Correlates among Saudi Women Attending Different Primary Health Centers.International journal of environmental research and public health · 2021
    Article
  2. Intracellular Signaling Cascades in Bipolar Disorder.Current topics in behavioral neurosciences · 2021
    Review
  3. Review
  4. Which CAM modalities are worth considering?The Journal of family practice · 2014
    Review
  5. Review
  6. Comorbidity between migraine and depression: update on traditional and alternative treatments.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2011
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

David MischoulonDepression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Suite 401, Boston, MA 02114, USA. dmischoulon@partners.org

Funding

Omega-3 Fatty Acids in the Treatment of DepressionK23AT001129 · NCCIH · MASSACHUSETTS GENERAL HOSPITAL · PI MISCHOULON, DAVID · 2001 to 2005
$817k
NCCIH NIH HHS 5K23AT001129-05NCCIH NIH HHS K23 AT001129
6 · The paper itself

Abstract

The popularity of natural or "alternative" remedies to treat medical and psychiatric disorders has accelerated dramatically over the past decade, in the United States and worldwide. This article reviews the evidence for clinical efficacy, active ingredients, mechanisms of action, recommended dosages, and toxicities of the 3 best-studied putative natural antidepressants, St. John's wort (hypericum), S-adenosyl methionine, and the Omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid. Despite growing evidence for efficacy and safety, more comprehensive studies are required before these remedies can be recommended as safe and effective alternatives or adjuncts to conventional psychotropic agents. There are limited data regarding safety in pregnancy and during lactation, and caution is therefore recommended in women who are pregnant or breastfeeding.

Indexed as

HypericumPhytotherapyAntidepressive AgentsComplementary TherapiesDepressionDocosahexaenoic AcidsEicosapentaenoic AcidFatty Acids, Omega-3FemaleHumansS-AdenosylmethionineAntidepressive AgentsDocosahexaenoic AcidsEicosapentaenoic AcidFatty Acids, Omega-3S-Adenosylmethionine

Identifiers

PMID19944301
PMCPMC2786903

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.