ArticleMicrobiology (Reading, England)2010
Identification of natural pneumococcal isolates expressing serotype 6D by genetic, biochemical and serological characterization.
Article in Microbiology (Reading, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
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Who cites it
64 citing papers in PubMed.
- Update on the evolving landscape of pneumococcal capsule types: new discoveries and way forward.Clinical microbiology reviews · 2025Review
- Implications of Cross-Reactivity and Cross-Protection for Pneumococcal Vaccine Development.Vaccines · 2024Review
- Bacterial capsules: Occurrence, mechanism, and function.NPJ biofilms and microbiomes · 2024Review
- Biochemical Characterization and Synthetic Application of WciN and Its Mutants FromFrontiers in chemistry · 2022Article
- High-throughput nanofluidic real-time PCR to discriminate Pneumococcal Conjugate Vaccine (PCV)-associated serogroups 6, 18, and 22 to serotypes using modified oligonucleotides.Scientific reports · 2021Article
- Pneumococci Can Become Virulent by Acquiring a New Capsule From Oral Streptococci.The Journal of infectious diseases · 2020Article
- A Population-Based Descriptive Atlas of Invasive Pneumococcal Strains Recovered Within the U.S. During 2015-2016.Frontiers in microbiology · 2018Article
- Screening assay for inhibitors of a recombinant Streptococcus pneumoniae UDP-glucose pyrophosphorylase.Journal of enzyme inhibition and medicinal chemistry · 2017Article
- Position of O-Acetylation within the Capsular Repeat Unit Impacts the Biological Properties of Pneumococcal Serotypes 33A and 33F.Infection and immunity · 2017Article
- Discovery of Novel Pneumococcal Serotype 35D, a Natural WciG-Deficient Variant of Serotype 35B.Journal of clinical microbiology · 2017Article
- Observational
- Serotype distribution and antimicrobial resistance of Streptococcus pneumoniae in children with acute bacterial meningitis in Mozambique: implications for a national immunization strategy.BMC microbiology · 2016Article
- Effects of PCV7 and PCV13 on invasive pneumococcal disease and carriage in Stockholm, Sweden.The European respiratory journal · 2016Article
- Pneumococcal Capsules and Their Types: Past, Present, and Future.Clinical microbiology reviews · 2015Review
- Genomics Reveals the Worldwide Distribution of Multidrug-Resistant Serotype 6E Pneumococci.Journal of clinical microbiology · 2015Article
- Bacterial Extracellular Polysaccharides in Biofilm Formation and Function.Microbiology spectrum · 2015Review
- Five winters of pneumococcal serotype replacement in UK carriage following PCV introduction.Vaccine · 2015Article
- Genetic, biochemical, and serological characterization of a new pneumococcal serotype, 6H, and generation of a pneumococcal strain producing three different capsular repeat units.Clinical and vaccine immunology : CVI · 2015Article
- Selective and genetic constraints on pneumococcal serotype switching.PLoS genetics · 2015Article
- Detection and serotyping of pneumococci in community acquired pneumonia patients without culture using blood and urine samples.BMC infectious diseases · 2015Article
4 more citing papers are in PubMed but not listed here.
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5 authors.
Funding
Abstract
The recently discovered pneumococcal serotype 6C was created when the original wciN gene in the 6A capsule gene locus was naturally replaced with a new gene. Since the capsule gene loci of 6A and 6B serotypes may differ by only one base pair in the wciP gene, it was speculated that a new serotype '6D' would be possible if the new wciN gene were inserted into the 6B capsule gene locus. Although pneumococci expressing serotype 6D could be produced in the laboratory, initial searches for natural pneumococcal isolates expressing serotype 6D were unsuccessful. However, we now report the discovery of two naturally occurring pneumococcal isolates from Korea that have the serological, genetic and biochemical features predicted for serotype 6D.
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