Evidence map›Paper›PMID 19942438›Full record

ReviewTrends in microbiology2010

Sense and sensibility: flagellum-mediated gene regulation.

Jennifer K Anderson, Todd G Smith, Timothy R Hoover

Abstract readReview
In one paragraph

Review in Trends in microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 100 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Virulence regulation in the fish pathogenFrontiers in cellular and infection microbiology · 2026
    Review
  5. Enrichment of vitamin BMicrobiome · 2025
    Article
  6. Article
  7. Article
  8. Direct sensing of host ferric iron by an archetype histidine kinase mediates virulence of an enteric pathogen.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. mBio · 2019
    Article
  17. Review
  18. Review
  19. Article
  20. Applied and environmental microbiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jennifer K AndersonDepartment of Microbiology, University of Georgia, Athens, Georgia 30602, USA.
Todd G Smith
Timothy R Hoover
University of Georgia · US

Funding

Transcriptional Control of the Helicobacter pylori RpoN RegulonR03AI080923 · NIAID · UNIVERSITY OF GEORGIA · PI HOOVER, TIMOTHY RANDALL · 2009 to 2010
$147k
NIAID NIH HHS AI080923NIAID NIH HHS R03 AI080923
6 · The paper itself

Abstract

The flagellum, a rotary engine required for motility in many bacteria, plays key roles in gene expression. It has been known for some time that flagellar substructures serve as checkpoints that coordinate flagellar gene expression with assembly. Less well understood, however, are other more global effects on gene expression. For instance, the flagellum acts as a 'wetness' sensor in Salmonella typhimurium, and as a mechanosensor in other bacteria. Additionally, it has been implicated in a variety of bacterial processes, including biofilm formation, pathogenesis and symbiosis. Although for many of these processes it might be simply that motility is required, in other cases it seems that the flagellum plays an underappreciated role in regulating gene expression.

Indexed as

Gene Expression Regulation, BacterialBacterial ProteinsCaulobacter crescentusEpsilonproteobacteriaFlagellaSalmonella typhimuriumSigma FactorBacterial ProteinsFliA protein, BacteriaSigma Factor

Identifiers

PMID19942438
PMCPMC2818477
OpenAlexW1990102687

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.