ArticleVaccine2010
A purified recombinant baculovirus expressed capsid protein of a new astrovirus provides partial protection to runting-stunting syndrome in chickens.
Article in Vaccine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 39 citations in OpenAlex.
- Maternal antibody-mediated protection against chicken astrovirus: efficacy of novel inactivated vaccine.Veterinary research communications · 2026Article
- A recombinant adenoviral vector vaccine expressing the ORF2 capsid protein confers robust protection against chicken astrovirus infection.Veterinary research · 2026Article
- Chicken Astro virus (CAstV): Isolation and characterization of new strains in broiler flocks with poor performance.Veterinary research communications · 2023Article
- Article
- An Insight into the Molecular Characteristics and Associated Pathology of Chicken Astroviruses.Viruses · 2022Review
- Structural Insights into the Human Astrovirus Capsid.Viruses · 2021Review
- Article
- Review
- Development and evaluation of two subunit vaccine candidates containing antigens of hepatitis E virus, rotavirus, and astrovirus.Scientific reports · 2016Article
- Detection of antibodies against Turkey astrovirus in humans.PloS one · 2014Article
- Molecular survey of enteric viruses in commercial chicken farms in Korea with a history of enteritis.Poultry science · 2013Article
- Article
- Histopathological studies on stunting syndrome in broilers, lahore, pakistan.Veterinary medicine international · 2013Article
- Determination of the full length sequence of a chicken astrovirus suggests a different replication mechanism.Virus genes · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A new viral sequence likely belonging to a virus of the family Astroviridae was determined using the gut content of chickens affected with the runting-stunting syndrome (RSS) in chickens. Since the appropriate virus could not be isolated in cell culture the open reading frame of the viral capsid protein was cloned to generate a recombinant baculovirus. The protein was purified and used as an experimental vaccine in broiler breeders to provide maternal derived antibodies for the protection of the offspring. The presence of specific antibodies was monitored by an ELISA. The offspring of vaccinated breeder hens were partially protected in a RSS challenge model.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.