SynthesisIntensive care medicine2010
Systematic review of paediatric alert criteria for identifying hospitalised children at risk of critical deterioration.
Synthesis in Intensive care medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Paediatric early warning systems for detecting and responding to clinical deterioration in children: a systematic review.BMJ open · 2017Pooled it
- Facilitators and barriers to quality of care in maternal, newborn and child health: a global situational analysis through metareview.BMJ open · 2014Pooled it
- Trial
- Trial
- Optimizing Pediatric Intermediate Care: Clinical Predictors of Deterioration and Length of Stay in a Tertiary Setting.Journal of clinical medicine · 2025Article
- Cautiously optimistic: paediatric critical care nurses' perspectives on data-driven algorithms in low-resource settings-a human-centred design study in Malawi.BMC global and public health · 2024Article
- Study protocol of a national multicentre prospective evaluation study assessing the validity and impact of the Dutch Paediatric Early Warning Score (PEWS) in the Netherlands.BMJ paediatrics open · 2024Article
- Signs and symptoms, apart from vital signs, that trigger nurses' concerns about deteriorating conditions in hospitalized paediatric patients: A scoping review.Nursing open · 2022Article
- Scoring system for activation of critical care air transport team for aeromedical evacuation.Medical journal, Armed Forces India · 2021Article
- How to implement a PEWS in a resource-limited setting: A quantitative analysis of the bedside-PEWS implementation in a hospital in northeast Brazil.Tropical medicine & international health : TM & IH · 2021Article
- Qualitative Study of Pediatric Early Warning Systems' Impact on Interdisciplinary Communication in Two Pediatric Oncology Hospitals With Varying Resources.JCO global oncology · 2020Article
- Use of paediatric early warning scores in intermediate care units.Archives of disease in childhood · 2020Observational
- Risk stratification to improve Pediatric Early Warning Systems: it is all about the context.European journal of pediatrics · 2019Article
- The Association Between Fever and Subsequent Deterioration Among Hospitalized Children With Elevated PEWS.Hospital pediatrics · 2019Article
- Do paediatric early warning scores relate to emergency department outcomes for children aged 0-2 years brought in by ambulance?British paramedic journal · 2019Article
- Scoping Review of Pediatric Early Warning Systems (PEWS) in Resource-Limited and Humanitarian Settings.Frontiers in pediatrics · 2018Article
- Salivary biomarkers may measure stress responses in critically ill children.SAGE open medicine · 2018Article
- Integration of Single-Center Data-Driven Vital Sign Parameters into a Modified Pediatric Early Warning System.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2017Article
- Diagnostic accuracy of PAT-POPS and ManChEWS for admissions of children from the emergency department.Emergency medicine journal : EMJ · 2016Article
- Reviewing the Evidence Base for the Children and Young People Safety Thermometer (CYPST): A Mixed Studies Review.Healthcare (Basel, Switzerland) · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionUnrecognised or untreated clinical deterioration can lead to serious adverse events, including cardiopulmonary arrest and unexpected death. Paediatric alert criteria aim to identify children with early signs of physiological instability that precede clinical deterioration so that experienced clinicians can intervene with the aim of reducing serious adverse events and improving outcome. PURPOSE: To identify the number and nature of published paediatric alert criteria and evaluate their validity, reliability, clinical effectiveness and clinical utility.
methodSystematic review of studies identified from electronic and citation searching and expert informants.
resultsEleven studies fulfilled the inclusion criteria and described ten paediatric alert criteria. Six studies described the introduction and use of the paediatric alert criteria in practice, four examined the development and testing of the paediatric alert criteria, and one described both. There was marked variability across all aspects of the paediatric alert criteria, including the method of development, and the number and type of component parameters. Five studies explored the predictive validity of the paediatric alert criteria, but only three reported appropriate methodology. Only one study evaluated reliability, and none evaluated clinical utility of paediatric alert criteria.
conclusionsEvidence supporting the validity, reliability and utility of paediatric alert criteria is weak. Studies are needed to determine which physiological parameters or combinations of parameters, best predict serious adverse events. Prospective evaluation of validity, reliability and utility is then needed before widespread adoption into clinical practice can be recommended.
Indexed as
Identifiers
19940976What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.