Evidence map›Paper›PMID 19940057›Full record

ArticleJournal of clinical microbiology2010

Molecular characteristics of occult hepatitis B virus from blood donors in southeast China.

Quan Yuan, Shan-Hai Ou, Chang-Rong Chen, Sheng-Xiang Ge, Bin Pei, Qing-Rui Chen, Qiang Yan, Yong-Cai Lin, Hong-Ying Ni, Cheng-Hao Huang and 4 more

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Occult hepatitis B virus infection.Nature reviews. Gastroenterology & hepatology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Quan YuanNational Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Science, Xiamen University, Xiamen, Fujian Province, China.
Shan-Hai Ou
Chang-Rong Chen
Sheng-Xiang Ge
Bin Pei
Qing-Rui Chen
Qiang Yan
Yong-Cai Lin
Hong-Ying Ni
Cheng-Hao Huang
Anthony E T Yeo
James W K Shih
Jun Zhang
Ning-Shao Xia

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The characteristics of 30 carriers with occult hepatitis B virus (HBV) infection (OBI) were compared with those of 30 individuals diagnosed as being HBV carriers at the time of blood donation, 60 asymptomatic carriers, and 60 chronic hepatitis patients. The prevalence of genotype C was significantly higher in carriers with OBIs than in any other HBsAg-positive (HBsAg(+)) group (P < 0.001). Specific amino acid substitutions in the regions from amino acids 117 to 121 and amino acids 144 to 147 located in the major hydrophilic region of the S gene were associated with carriers with OBIs (P < 0.01 for carriers with OBIs versus HBsAg(+) donors, carriers with OBIs versus HBsAg(+) asymptomatic carriers, and carriers with OBIs versus HBsAg(+) chronic hepatitis patients). G145R was the major variation in the HBV isolates responsible for local occult HBV infections.

Indexed as

Blood DonorsAdultAmino Acid SequenceAmino Acid SubstitutionCarrier StateChinaDNA, ViralFemaleGenotypeHepatitis BHepatitis B, ChronicHepatitis B Surface AntigensHepatitis B virusHumansMaleMolecular Sequence DataDNA, ViralHepatitis B Surface Antigens

Identifiers

PMID19940057
PMCPMC2815617

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.