ArticleJournal of psychopharmacology (Oxford, England)2010
During pregnancy, recreational drug-using women stop taking ecstasy (3,4-methylenedioxy-N-methylamphetamine) and reduce alcohol consumption, but continue to smoke tobacco and cannabis: initial findings from the Development and Infancy Study.
Article in Journal of psychopharmacology (Oxford, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 104 citations in OpenAlex.
- Cannabis Use in Pregnancy and Neonatal Outcomes: A Systematic Review and Meta-Analysis.Cannabis and cannabinoid research · 2024Pooled it
- Birth Outcomes of Neonates Exposed to Marijuana in Utero: A Systematic Review and Meta-analysis.JAMA network open · 2022Pooled it
- Abstinence outcomes among women in reproductive health centers administered clinician or electronic brief interventions.Journal of substance abuse treatment · 2020Trial
- Motivational enhancement therapy coupled with cognitive behavioral therapy versus brief advice: a randomized trial for treatment of hazardous substance use in pregnancy and after delivery.General hospital psychiatryTrial
- Prenatal cannabis use is associated with altered miRNA and protein expression in the developing human brain.Journal of psychopharmacology (Oxford, England) · 2026Article
- Child and maternal health outcomes following antenatal exposure to classic psychedelic substances: a systematic review.Research square · 2026Article
- Psychedelic exposure in pregnancy: a scoping review to inform perinatal drug safety and clinical counseling.Therapeutic advances in drug safety · 2026Review
- Typologies of Maternal Substance Use in Pregnancy: Latent Classes and Sociodemographic Correlates in a U.S. Sample.Journal of studies on alcohol and drugs · 2025Article
- Article
- Prenatal cannabis exposure in the clinic and laboratory: What do we know and where do we need to go?Drug and alcohol dependence reports · 2024Review
- Fetal Cannabinoid Syndrome: Behavioral and Brain Alterations of the Offspring Exposed to Dronabinol during Gestation and Lactation.International journal of molecular sciences · 2024Article
- Marijuana Use among Pregnant and Nonpregnant Women of Reproductive Age, 2013-2019.Substance use & misuse · 2024Article
- Prenatal delta-9-tetrahydrocannabinol exposure is associated with changes in rhesus macaque DNA methylation enriched for autism genes.Clinical epigenetics · 2023Article
- An epigenetic synopsis of parental substance use.Epigenomics · 2023Review
- Limited Utility of Toxicology Testing at Delivery for Perinatal Cannabis Use.Hospital pediatrics · 2023Article
- Licit and illicit drug use across trimesters in pregnant women endorsing past-year substance use: Results from National Survey on Drug Use and Health (2009-2019).Archives of women's mental health · 2022Article
- Prenatal Exposure to Delta-9-tetrahydrocannabinol (THC) Alters the Expression of miR-122-5p and Its TargetInternational journal of molecular sciences · 2022Article
- The Impact of Early Life Exposure to Cannabis: The Role of the Endocannabinoid System.International journal of molecular sciences · 2021Review
- Association between maternal cannabis use and birth outcomes: an observational study.BMC pregnancy and childbirth · 2020Observational
- Fifty Years of Research on Prenatal Substances: Lessons Learned for the Opioid Epidemic.Adversity and resilience science · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 2 countries.
Funding
Abstract
While recreational drug use in UK women is prevalent, to date there is little prospective data on patterns of drug use in recreational drug-using women immediately before and during pregnancy. A total of 121 participants from a wide range of backgrounds were recruited to take part in the longitudinal Development and Infancy Study (DAISY) study of prenatal drug use and outcomes. Eighty-six of the women were interviewed prospectively while pregnant and/or soon after their infant was born. Participants reported on use immediately before and during pregnancy and on use over their lifetime. Levels of lifetime drug use of the women recruited were high, with women reporting having used at least four different illegal drugs over their lifetime. Most users of cocaine, 3,4-methylenedioxy-N-methylamphetamine (MDMA) and other stimulants stopped using these by the second trimester and levels of use were low. However, in pregnancy, 64% of the sample continued to use alcohol, 46% tobacco and 48% cannabis. While the level of alcohol use reduced substantially, average tobacco and cannabis levels tended to be sustained at pre-pregnancy levels even into the third trimester (50 cigarettes and/or 11 joints per week). In sum, while the use of 'party drugs' and alcohol seems to reduce, levels of tobacco and cannabis use are likely to be sustained throughout pregnancy. The data provide polydrug profiles that can form the basis for the development of more realistic animal models.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.