ArticleGenome medicine2009
Sex chromosomes and genetic association studies.
Article in Genome medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review of analytical methods used in genetic association analysis of the X-chromosome.Briefings in bioinformatics · 2022Pooled it
- Genes in the pathway of tooth mineral tissues and dental caries risk: a systematic review and meta-analysis.Clinical oral investigations · 2020Pooled it
- X-chromosomal genetic variants and haplotype analysis in male cerebral palsy patients: insights into genetic susceptibility and sex-specific risk.Journal of neurodevelopmental disorders · 2026Article
- X-chromosome-wide association study for Alzheimer's disease.Molecular psychiatry · 2025Article
- An X Chromosome Transcriptome Wide Association Study Implicates ARMCX6 in Alzheimer's Disease.bioRxiv : the preprint server for biology · 2023Article
- eXclusionarY: 10 years later, where are the sex chromosomes in GWASs?American journal of human genetics · 2023Review
- Article
- The X factor: A robust and powerful approach to X-chromosome-inclusive whole-genome association studies.Genetic epidemiology · 2021Article
- Social environment and genetics underlie body site-specific microbiomes of Yellowstone National Park gray wolves (Ecology and evolution · 2021Article
- Sarcoptic mange severity is associated with reduced genomic variation and evidence of selection in Yellowstone National Park wolves (Evolutionary applications · 2021Article
- Review
- A robust test for X-chromosome genetic association accounting for X-chromosome inactivation and imprinting.Genetics research · 2020Article
- A statistical measure for the skewness of X chromosome inactivation based on case-control design.BMC bioinformatics · 2019Article
- Statistics for X-chromosome associations.Genetic epidemiology · 2018Article
- The Polymorphisms atGastroenterology research and practice · 2018Article
- Pharmacogenetics of methylphenidate in childhood attention-deficit/hyperactivity disorder: long-term effects.Scientific reports · 2017Article
- Trauma-Induced Acute X Chromosome Skewing in White Blood Cells Represents an Immuno-Modulatory Mechanism Unique to Females and a Likely Contributor to Sex-Based Outcome Differences.Shock (Augusta, Ga.) · 2017Article
- Inherent X-Linked Genetic Variability and Cellular Mosaicism Unique to Females Contribute to Sex-Related Differences in the Innate Immune Response.Frontiers in immunology · 2017Article
- Modeling X Chromosome Data Using Random Forests: Conquering Sex Bias.Genetic epidemiology · 2016Article
- Variants of MicroRNA Genes: Gender-Specific Associations with Multiple Sclerosis Risk and Severity.International journal of molecular sciences · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the literature concerning statistical testing for genotype-phenotype association in family-based and population-based studies is very extensive, until recently the sex chromosomes have received little attention. Here it is shown that the X chromosome in particular presents special problems with respect to efficient analysis of mixed-sex population studies, and as a result of X inactivation. This paper reviews recent developments in approaching these problems.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.