ArticleAnalytical chemistry2010
Differential ion mobility separations of peptides with resolving power exceeding 50.
Article in Analytical chemistry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Oxygen enhanced plasma discharge and its application as carrier gas for high-field asymmetric ion mobility spectroscopy.Analytical and bioanalytical chemistry · 2025Article
- The Effect of Co-Culture with DifferentFoods (Basel, Switzerland) · 2024Article
- Variables Affecting the Internal Energy of Peptide Ions During Separation by Differential Ion Mobility Spectrometry.Journal of the American Society for Mass Spectrometry · 2017Article
- Ion Mobility Separation of Peptide Isotopomers.Journal of the American Society for Mass Spectrometry · 2016Article
- To What Extent is FAIMS Beneficial in the Analysis of Proteins?Journal of the American Society for Mass Spectrometry · 2016Article
- Decreased Gap Width in a Cylindrical High-Field Asymmetric Waveform Ion Mobility Spectrometry Device Improves Protein Discovery.Analytical chemistry · 2015Article
- Improved Differential Ion Mobility Separations Using Linked Scans of Carrier Gas Composition and Compensation Field.Journal of the American Society for Mass Spectrometry · 2015Article
- Optimization of peptide separations by differential ion mobility spectrometry.Journal of the American Society for Mass Spectrometry · 2014Article
- Pushing the Frontier of High-Definition Ion Mobility Spectrometry Using FAIMS.Mass spectrometry (Tokyo, Japan) · 2013Article
- High-definition differential ion mobility spectrometry with resolving power up to 500.Journal of the American Society for Mass Spectrometry · 2013Article
- High-field asymmetric waveform ion mobility spectrometry for mass spectrometry-based proteomics.Expert review of proteomics · 2012Review
- Conformational distribution of bradykinin [bk + 2 H]2+ revealed by cold ion spectroscopy coupled with FAIMS.Journal of the American Society for Mass Spectrometry · 2012Article
- Ion mobility separation of variant histone tails extending to the "middle-down" range.Analytical chemistry · 2012Article
- Accelerated high-resolution differential ion mobility separations using hydrogen.Analytical chemistry · 2011Article
- Separation of a set of peptide sequence isomers using differential ion mobility spectrometry.Analytical chemistry · 2011Article
- Separation and classification of lipids using differential ion mobility spectrometry.Journal of the American Society for Mass Spectrometry · 2011Article
- Ion mobility separation of isomeric phosphopeptides from a protein with variant modification of adjacent residues.Analytical chemistry · 2011Article
- Size, weight and position: ion mobility spectrometry and imaging MS combined.Analytical and bioanalytical chemistry · 2011Review
- Ultrahigh-resolution differential ion mobility spectrometry using extended separation times.Analytical chemistry · 2011Article
- Separation of peptide isomers with variant modified sites by high-resolution differential ion mobility spectrometry.Analytical chemistry · 2010Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Differential ion mobility spectrometry (IMS) or field asymmetric waveform IMS (FAIMS) separates gas-phase ions by mobility differences with respect to the electric field intensity. A major emerging FAIMS application is the fractionation of proteolytic digests. Using a planar FAIMS unit with helium/nitrogen mixtures, we have increased FAIMS resolving powers for peptide analyses from the prior maximum of approximately 20-30 to approximately 50-70. The resolution improved nearly 3-fold, allowing, in particular, separation of previously unresolved conformers.
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Registered trials
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