ArticleWorld journal of gastroenterology2009
Analysis of monocyte chemotactic protein-1 gene polymorphism in patients with spontaneous bacterial peritonitis.
Article in World journal of gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- A Double-Blind, Randomized Placebo-Controlled Trial of ProbioticNutrients · 2020Trial
- Liver cirrhosis and immune dysfunction.International immunology · 2022Review
- Cirrhotics with Monocyte Chemotactic Protein 1 Polymorphism are at Higher Risk for Developing Spontaneous Bacterial Peritonitis - A Cohort Study.Journal of clinical and translational research · 2021Article
- Immunotherapy in hepatocellular carcinoma: the complex interface between inflammation, fibrosis, and the immune response.Journal for immunotherapy of cancer · 2019Review
- Genetic variants of TRAF6 modulate peritoneal immunity and the risk of spontaneous bacterial peritonitis in cirrhosis: A combined prospective-retrospective study.Scientific reports · 2017Article
- Immune Dysfunction in Cirrhosis.Journal of clinical and translational hepatology · 2017Review
- Ascites' neutrophil function is significantly impaired in patients with decompensated cirrhosis but can be restored by autologous plasma incubation.Scientific reports · 2016Article
- Spontaneous bacterial peritonitis: The clinical challenge of a leaky gut and a cirrhotic liver.World journal of hepatology · 2015Review
- Molecular detection of monocyte chemotactic protein-1 polymorphism in spontaneous bacterial peritonitis patients.World journal of gastroenterology · 2014Article
- Immune dysfunction in cirrhosis.World journal of gastroenterology · 2014Review
- Risk factors and outcome of bacterial infections in cirrhosis.World journal of gastroenterology · 2014Review
- Hepatic expression of CCL2 in alcoholic liver disease is associated with disease severity and neutrophil infiltrates.Clinical and experimental immunology · 2012Article
- Monocyte chemotactic protein-1 gene polymorphism and spontaneous bacterial peritonitis.World journal of gastroenterology · 2010Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate a genetic polymorphism of the monocyte chemotactic protein-1 (MCP-1) gene in patients with spontaneous bacterial peritonitis (SBP).
methodsMCP-1 genotyping was performed in 23 patients with SBP and 83 cirrhotic control patients with non-infected ascites.
resultsThe frequency of carriers of the G-allele was lower in SBP patients but this difference did not reach statistical significance. However, in the subgroup of patients with alcoholic cirrhosis (n = 80), carriers of the G-allele were significantly less frequent in SBP-patients (38.1%) than in cirrhotic controls (67.8%, P = 0.021).
conclusionIn patients with alcoholic liver cirrhosis, the -2518 MCP-1 genotype AA is a risk factor for the development of SBP.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.