ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2010
Low bone mineral density is not associated with angiographically determined coronary atherosclerosis in men.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Pooled it
- Osteoporosis and Coronary Artery Disease Burden in Older Adults with Chronic Coronary Syndrome: A Two-Center Cross-Sectional Study in Vietnam.Journal of clinical medicine · 2026Article
- Low bone mineral density and coronary artery disease: A systematic review and meta-analysis.International journal of cardiology. Heart & vasculature · 2021Review
- Associations between bone mineral density in different measurement locations and coronary artery disease: a cross-sectional study.Archives of osteoporosis · 2021Article
- Low bone mineral density is associated with global coronary atherosclerotic plaque burden in stable angina patients.Clinical interventions in aging · 2018Article
- Association factor analysis between osteoporosis with cerebral artery disease: The STROBE study.Medicine · 2017Article
- Osteoporosis and atherosclerosis: a post-mortem MDCT study of an elderly cohort.European radiology · 2013Article
- Bone mineral density and coronary atherosclerosis.Journal of the Saudi Heart Association · 2011Article
- Vascular calcification and fracture risk.Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal DiseasesReview
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledThis study for the first time investigates the association of bone mineral density (BMD) with angiographically determined coronary atherosclerosis in men. Our data show that the prevalence of low BMD is very high in men undergoing coronary angiography. However, neither osteopenia nor osteoporosis is associated with an increased prevalence of angiographically determined coronary atherosclerosis.
introductionThe association of low BMD with angiographically determined coronary atherosclerosis in men is unknown.
methodsWe enrolled 623 consecutive men undergoing coronary angiography for the evaluation of established or suspected coronary artery disease (CAD). BMD was assessed by dual X-ray absorptiometry. CAD was diagnosed in the presence of any coronary artery lumen narrowing at angiography; coronary stenoses with lumen narrowing > or =50% were considered significant.
resultsFrom the total study cohort (mean age of 64 +/- 11 years), 207 patients (33.2%) had osteopenia and 65 (10.4%) had osteoporosis; at angiography, CAD was diagnosed in 558 patients (89.6%) and 403 (64.7%) had significant coronary stenoses. In multivariate logistic regression analysis neither osteopenia nor osteoporosis was associated with an increased prevalence of CAD (adjusted odds ratios (ORs) = 0.71 [95% confidence interval 0.40-1.23]; p = 0.222 and 1.03 [0.38-2.80]; p = 0.955, respectively) or with significant coronary stenoses (OR 0.74 [0.52-1.07], p = 0.112 and 0.72 [0.41-1.26]; p = 0.251, respectively). Also, as a continuous variable, BMD was not associated with angiographically diagnosed CAD.
conclusionsThe prevalence of low BMD is very high in men undergoing coronary angiography. However, low BMD is not associated with angiographically determined coronary atherosclerosis in men.
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