Trial reportPsychopharmacology2010
Are attention lapses related to d-amphetamine liking?
Trial report in Psychopharmacology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Drug liking and wanting, not impulsive action or reflection is increased by 4-fluoroamphetamine.Psychopharmacology · 2018Trial
- Test-retest reliability of behavioral measures of impulsive choice, impulsive action, and inattention.Experimental and clinical psychopharmacology · 2013Trial
- Inattention, impulsive action, and subjective response to D-amphetamine.Drug and alcohol dependence · 2013Trial
- Effect of D-amphetamine on inhibition and motor planning as a function of baseline performance.Psychopharmacology · 2010Trial
- Attention-deficit hyperactivity disorder (ADHD) stimulant medications as cognitive enhancers.Frontiers in neuroscience · 2013Article
- Are executive function and impulsivity antipodes? A conceptual reconstruction with special reference to addiction.Psychopharmacology · 2012Review
- Response inhibition impairments predict alcohol-induced sedation.Alcohol and alcoholism (Oxford, Oxfordshire)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
rationaleA rich literature suggests that both impulsiveness and drug-induced euphoria are risk factors for drug abuse. However, few studies have examined whether sensitivity to the euphoric effects of stimulants is related to attention lapses, a behavioral measure of inattention sometimes associated with impulsivity.
objectiveThe aim of the study was to examine ratings of d-amphetamine drug liking among individuals with high, moderate, and low attention lapses.
methodsNinety-nine healthy volunteers were divided into three equal-sized groups based on their performance on a measure of lapses of attention. The groups, who exhibited low, medium, and high attention lapses (i.e., long reaction times) on a simple reaction time task, were compared on their subjective responses (i.e., ratings of liking and wanting more drug) after acute doses of d-amphetamine (0, 5, 10, and 20 mg).
resultsSubjects who exhibited high lapses liked 20 mg d-amphetamine less than subjects who exhibited low lapses. These subjects also tended to report smaller increases in "wanting more drug" after d-amphetamine.
conclusionThe findings suggest that participants who exhibit impaired attention may be less sensitive to stimulant-induced euphoria.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.