ArticleIndian journal of pediatrics2009
Serum thyroid hormone profile in critically Ill children.
Article in Indian journal of pediatrics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed.
- Non-thyroidal Illness in Children with Congestive Heart FailureJournal of clinical research in pediatric endocrinology · 2024Article
- Thyroid Hormone Profile in Children with Sepsis: Does Euthyroid Sick Syndrome Exist?Open access Macedonian journal of medical sciences · 2019Article
- Low triiodothyronine predicts mortality in critically ill patients.Indian journal of endocrinology and metabolism · 2013Article
- Article
- Thyroid function status and its impact on clinical outcome in patients admitted to critical care.Pakistan journal of medical sciencesArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo study thyroid hormone profile in critically ill children and its correlation to disease severity and clinical outcome.
methodsTotal serum triiodothyronine (T3), thyroxine (T4) and TSH were estimated at admission and discharge from PICU/ just before death.
resultsMean T3 levels in cases were significantly lower than controls and lower in patients who expired, both at admission and just prior to death. Mean T4 levels were lower in cases, and just prior to death. Mean TSH levels were not different in cases and controls; or in survived and expired cases. When both T3 and T4 are low, mortality risk increases 30 times. Serum T3, T4 and TSH values improved in patients who survived unlike in those who expired. Age, sex, duration of hospital stay, ventilation, inotropic support, and PICU stay did not show any correlation with patient outcome or thyroid hormone profile. PRISM score at 24 hours and T4 levels in the second sample were significant predictors of survival.
conclusionT3 levels reflect the patient's clinical status, T4 levels can predict survival.
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Identifiers
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Registered trials
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