Evidence map›Paper›PMID 19936577›Full record

ReviewDer Anaesthesist2010

[Old and new anticoagulants. Antidotes and measures for acute hemorrhaging and urgent interventions].

M Lancé, B Stessel, K Hamulyák, M A Marcus

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Der Anaesthesist, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 8 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

M LancéKlinik für Anästhesiologie und Schmerztherapie, Universitätsklinikum MUMC+, AZ Maastricht, The Netherlands. marcus.lance@mumc.nl
B Stessel
K Hamulyák
M A Marcus
LWL-Universitätsklinikum Bochum · DEMaastricht University Medical Centre · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anticoagulation medications are frequently used for primary and secondary treatment of several thrombo-embolic disorders. An important side effect of all anticoagulants is hemorrhagic diathesis which necessitates acute treatment, ideally using medicinal therapy with an antidote. Much experience has been gained in treating bleeding while on traditional anticoagulants, such as heparins and vitamin K antagonists by the use of antagonists. A multitude of factor-specific anticoagulants have recently been introduced or will soon receive approval. With this new generation of anticoagulants no valid laboratory parameters or effective antagonists are presently available. Due to a lack of adequate studies regarding acute treatment this can at present only be carried out on a symptomatic basis.

Indexed as

Acute DiseaseAnticoagulantsAntidotesFactor Xa InhibitorsHemorrhageHeparinHeparin AntagonistsHumansPolysaccharidesProthrombinVitamin KAnticoagulantsAntidotesFactor Xa InhibitorsHeparinHeparin AntagonistsPolysaccharidesProthrombinVitamin K

Identifiers

PMID19936577
OpenAlexW1588101269

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.