ArticlePLoS genetics2009
Diversity of Pol IV function is defined by mutations at the maize rmr7 locus.
Article in PLoS genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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43 citing papers in PubMed, 81 citations in OpenAlex.
- Identification of Proteins Associated with Stably Integrated MaizePlants (Basel, Switzerland) · 2025Article
- RNA-directed DNA methylation mutants reduce histone methylation at the paramutated maize booster1 enhancer.Plant physiology · 2024Article
- Paramutation at the maize pl1 locus is associated with RdDM activity at distal tandem repeats.PLoS genetics · 2024Article
- Transposition of HOPPLA in siRNA-deficient plants suggests a limited effect of the environment on retrotransposon mobility in Brachypodium distachyon.PLoS genetics · 2024Article
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- DNA-dependent RNA polymerases in plants.The Plant cell · 2023Article
- CHROMOMETHYLTRANSFERASE3/KRYPTONITE maintains theProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Reinforcement of CHH methylation through RNA-directed DNA methylation ensures sexual reproduction in rice.Plant physiology · 2022Article
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- The effect of RNA polymerase V on 24-nt siRNA accumulation depends on DNA methylation contexts and histone modifications in rice.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Polyploidy-associated paramutation in Arabidopsis is determined by small RNAs, temperature, and allele structure.PLoS genetics · 2021Article
- Locus-specific paramutation in Zea mays is maintained by a PICKLE-like chromodomain helicase DNA-binding 3 protein controlling development and male gametophyte function.PLoS genetics · 2020Article
- Evidence for a Unique DNA-Dependent RNA Polymerase in Cereal Crops.Molecular biology and evolution · 2018Article
- Paramutation-like features of multiple natural epialleles in tomato.BMC genomics · 2018Article
- The gymnastics of epigenomics in rice.Plant cell reports · 2018Review
- Altered nucleosome positions in maize haplotypes and mutants of a subset of SWI/SNF-like proteins.Plant direct · 2017Article
- Paramutation and related phenomena in diverse species.Nature reviews. Genetics · 2017Review
- Article
- RNA Pol IV and V in gene silencing: Rebel polymerases evolving away from Pol II's rules.Current opinion in plant biology · 2015Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mutations affecting the heritable maintenance of epigenetic states in maize identify multiple small RNA biogenesis factors including NRPD1, the largest subunit of the presumed maize Pol IV holoenzyme. Here we show that mutations defining the required to maintain repression7 locus identify a second RNA polymerase subunit related to Arabidopsis NRPD2a, the sole second largest subunit shared between Arabidopsis Pol IV and Pol V. A phylogenetic analysis shows that, in contrast to representative eudicots, grasses have retained duplicate loci capable of producing functional NRPD2-like proteins, which is indicative of increased RNA polymerase diversity in grasses relative to eudicots. Together with comparisons of rmr7 mutant plant phenotypes and their effects on the maintenance of epigenetic states with parallel analyses of NRPD1 defects, our results imply that maize utilizes multiple functional NRPD2-like proteins. Despite the observation that RMR7/NRPD2, like NRPD1, is required for the accumulation of most siRNAs, our data indicate that different Pol IV isoforms play distinct roles in the maintenance of meiotically-heritable epigenetic information in the grasses.
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