ArticleGene regulation and systems biology2007
Enterobacterial small mobile sequences carry open reading frames and are found intragenically--evolutionary implications for formation of new peptides.
Article in Gene regulation and systems biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 15 citations in OpenAlex.
- Review
- Co-Evolution of Opioid and Adrenergic Ligands and Receptors: Shared, Complementary Modules Explain Evolution of Functional Interactions and Suggest Novel Engineering Possibilities.Life (Basel, Switzerland) · 2021Article
- MITEmSphere · 2019Article
- Tumor grafting induces changes of gut microbiota in athymic nude mice in the presence and absence of medicinal Gynostemma saponins.PloS one · 2015Article
- Bacterial genome instability.Microbiology and molecular biology reviews : MMBR · 2014Review
- Detection and characterization of miniature inverted-repeat transposable elements in “Candidatus Liberibacter asiaticus”.Journal of bacteriology · 2013Article
- Novel miniature transposable elements in thermophilic Synechococcus strains and their impact on an environmental population.Journal of bacteriology · 2012Article
- Reductive divergence of enterobacterial repetitive intergenic consensus sequences among Gammaproteobacteria genomes.Journal of microbiology (Seoul, Korea) · 2011Article
- Impact of small repeat sequences on bacterial genome evolution.Genome biology and evolution · 2011Article
- Stem loop sequences specific to transposable element IS605 are found linked to lipoprotein genes in Borrelia plasmids.PloS one · 2009Article
- Intergenic regions of Borrelia plasmids contain phylogenetically conserved RNA secondary structure motifs.BMC genomics · 2009Article
- Small mobile sequences in bacteria display diverse structure/function motifs.Molecular microbiology · 2008Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intergenic repeat units of 127-bp (RU-1) and 168-bp (RU-2), as well as a newly-found class of 103-bp (RU-3), represent small mobile sequences in enterobacterial genomes present in multiple intergenic regions. These repeat sequences display similarities to eukaryotic miniature inverted-repeat transposable elements (MITE). The RU mobile elements have not been reported to encode amino acid sequences. An in silico approach was used to scan genomes for location of repeat units. RU sequences are found to have open reading frames, which are present in annotated gene loci whereby the RU amino acid sequence is maintained. Gene loci that display repeat units include those that encode large proteins which are part of super families that carry conserved domains and those that carry predicted motifs such as signal peptide sequences and transmembrane domains. A putative exported protein in Y. pestis and a phylogenetically conserved putative inner membrane protein in Salmonella species represent some of the more interesting constructs. We hypothesize that a major outcome of RU open reading frame fusions is the evolutionary emergence of new proteins.
Indexed as
Identifiers
19936088PMC2759123W1816133595What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.