ReviewBritish journal of cancer2010
Metabolic assessment of the action of targeted cancer therapeutics using magnetic resonance spectroscopy.
Review in British journal of cancer, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed.
- Preclinical Applications of Magnetic Resonance Imaging in Oncology.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026Review
- Non-invasive biomarkers for monitoring the immunotherapeutic response to cancer.Journal of translational medicine · 2020Review
- Current Methods of Magnetic Resonance for Noninvasive Assessment of Molecular Aspects of Pathoetiology in Multiple Sclerosis.International journal of molecular sciences · 2020Review
- Interplay between post-translational cyclooxygenase-2 modifications and the metabolic and proteomic profile in a colorectal cancer cohort.World journal of gastroenterology · 2019Article
- Metabolic biomarkers of response to the AKT inhibitor MK-2206 in pre-clinical models of human colorectal and prostate carcinoma.British journal of cancer · 2018Article
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- Article
- Breast Tissue Metabolism by Magnetic Resonance Spectroscopy.Metabolites · 2017Review
- Article
- Choline kinase alpha-Putting the ChoK-hold on tumor metabolism.Progress in lipid research · 2016Review
- Key Players in Choline Metabolic Reprograming in Triple-Negative Breast Cancer.Frontiers in oncology · 2016Review
- Neurochemical changes in the pericalcarine cortex in congenital blindness attributable to bilateral anophthalmia.Journal of neurophysiology · 2015Article
- Increased levels of choline metabolites are an early marker of docetaxel treatment response in BRCA1-mutated mouse mammary tumors: an assessment by ex vivo proton magnetic resonance spectroscopy.Journal of translational medicine · 2015Article
- Acquired resistance to EGFR tyrosine kinase inhibitors alters the metabolism of human head and neck squamous carcinoma cells and xenograft tumours.British journal of cancer · 2015Article
- Bifunctional chelates optimized for molecular MRI.Inorganic chemistry · 2014Article
- Monitoring response to cytostatic cisplatin in a HER2(+) ovary cancer model by MRI and in vitro and in vivo MR spectroscopy.British journal of cancer · 2014Article
- Monitoring chemotherapeutic response by hyperpolarized 13C-fumarate MRS and diffusion MRI.Cancer research · 2014Article
- High-field small animal magnetic resonance oncology studies.Physics in medicine and biology · 2014Review
- Article
- Principles of multiparametric optimization for phospholipidomics byBiophysical reviews · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Developing rational targeted cancer drugs requires the implementation of pharmacodynamic (PD), preferably non-invasive, biomarkers to aid response assessment and patient follow-up. Magnetic resonance spectroscopy (MRS) allows the non-invasive study of tumour metabolism. We describe the MRS-detectable PD biomarkers resulting from the action of targeted therapeutics, and discuss their biological significance and future translation into clinical use.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.