Evidence map›Paper›PMID 19935740›Full record

ReviewNature reviews. Cardiology2010

PET and SPECT in cardiovascular molecular imaging.

Lawrence W Dobrucki, Albert J Sinusas

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Cardiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03943966 (In-vivo Thrombus Imaging With 18F-GP1, a Novel Platelet PET Radiotracer), which is not on this map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03943966 nacompletednot on this mapstarted 2019, after this paper: background citation

In-vivo Thrombus Imaging With 18F-GP1, a Novel Platelet PET Radiotracer

TypeinterventionalSponsorUniversity of EdinburghRan2019 to 2021Enrolled73ConditionsThrombosis, Atherothrombosis, Myocardial Infarction, STEMIArms18F-GP1 PET CT
3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 168 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Exploring innovative strides in radiolabeled nanoparticle progress for multimodality cancer imaging and theranostic applications.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Review
  10. Article
  11. Review
  12. Review
  13. Recent Advances ofInternational journal of molecular sciences · 2023
    Review
  14. Article
  15. Increasing angular sampling through deep learning for stationary cardiac SPECT image reconstruction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  16. International journal of molecular sciences · 2022
    Article
  17. Review
  18. Article
  19. Review
  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lawrence W DobruckiSection of Cardiovascular Medicine, Department of Medicine and Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT 06520-8017, USA.
Albert J Sinusas
Yale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current focus of cardiovascular medicine is on early detection and prevention of disease, to control the escalating costs of health care. To achieve this goal, novel imaging approaches that allow for early detection of disease and risk stratification are needed. Traditionally, the diagnosis, monitoring, and prognostication of cardiovascular disease were based on techniques that measured changes in metabolism, blood flow, and biological function. Molecular imaging is emerging as a new tool for the noninvasive detection of biological processes that can differentiate and characterize tissues before manifestation of gross anatomical features or physiological consequences. Leading the way are techniques involving high-sensitivity radiotracers that could revolutionize current diagnostic paradigms. This Review provides an overview of selected molecular-based single photon emission CT (SPECT) and PET imaging strategies for the evaluation of cardiovascular disease-including the evaluation of myocardial metabolism and neurohumoral activity of the heart-and potential future targeted methods of evaluating critical molecular processes, such as atherosclerosis, ventricular remodeling after myocardial infarction, and ischemia-associated angiogenesis.

Indexed as

Cardiac-Gated Single-Photon Emission Computer-Assisted TomographyPositron-Emission TomographyAnimalsAtherosclerosisCardiovascular DiseasesCoronary Artery DiseaseGenes, ReporterHumansMolecular ImagingMyocardial InfarctionMyocardial IschemiaMyocardiumNeovascularization, PathologicPrognosisRisk AssessmentRisk Factors

Identifiers

PMID19935740
OpenAlexW2039193236

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.