Evidence map›Paper›PMID 19934356›Full record

ReviewProceedings of the American Thoracic Society2009

Bronchiolar progenitor cells.

Huaiyong Chen, Keitaro Matsumoto, Barry R Stripp

Open access · greenAbstract readReview
In one paragraph

Review in Proceedings of the American Thoracic Society, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Depletion of Airway Submucosal Glands and TP63American journal of respiratory and critical care medicine · 2018
    Article
  2. Article
  3. Article
  4. Article
  5. Stem cell applications in military medicine.Stem cell research & therapy · 2011
    Review
  6. Review
  7. Article
  8. Stem cells and cell therapies in lung biology and lung diseases.Proceedings of the American Thoracic Society · 2011
    Article
  9. Evidence for human lung stem cells.The New England journal of medicine · 2011
    Article
  10. Article
  11. Review
  12. Stem cells and cell therapy approaches in lung biology and diseases.Translational research : the journal of laboratory and clinical medicine · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Huaiyong ChenDivision of Pulmonary, Allergy and Critical Care Medicine, Duke University Medical Center, 106 Research Drive, Durham, NC 27710, USA.
Keitaro Matsumoto
Barry R Stripp
Duke University · USDuke Medical Center · US

Funding

STEM CELLS IN AIRWAY REPAIRR01HL064888 · NHLBI · UNIVERSITY OF ROCHESTER · PI STRIPP, BARRY R · 2000 to 2009
$3.1M
Stem Cells to Enhance Bronchiolar Reparative Capacity.R01HL090146 · NHLBI · DUKE UNIVERSITY · PI STRIPP, BARRY R · 2007 to 2010
$2.6M
Methods for the amplification and identification of airway stem cellsR21HL089141 · NHLBI · DUKE UNIVERSITY · PI STRIPP, BARRY R · 2009 to 2010
$429k
NHLBI NIH HHS HL064888NHLBI NIH HHS HL089141NHLBI NIH HHS HL090146
6 · The paper itself

Abstract

A comprehensive appreciation of mechanisms regulating epithelial maintenance and repair in pulmonary airways is fundamental to our understanding of tissue remodeling and dysfunction in chronic lung disease. This review provides an update on current concepts that have emerged from recent work in the field of airway epithelial repair and progenitor cell biology. New models to investigate the behavior of lung epithelial progenitor cells have provided fresh insights into their regulation and organization, and help to clarify their roles in normal maintenance and repair. Emerging technologies for the fractionation and culture of lung epithelial cells also provide opportunities to investigate the behavior and regulation of progenitor cell subsets in controlled systems. These advances hold promise for development of new strategies to modulate epithelial cell behavior and to effect tissue repair in the setting of lung disease.

Indexed as

BronchiHumansPulmonary Disease, Chronic ObstructiveRespiratory MucosaStem Cells

Identifiers

PMID19934356
PMCPMC3266052
OpenAlexW2086875105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.