ReviewProceedings of the American Thoracic Society2009
Hormonal influences on lung function and response to environmental agents: lessons from animal models of respiratory disease.
Review in Proceedings of the American Thoracic Society, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Incidence and influencing factors of occupational pneumoconiosis: a systematic review and meta-analysis.BMJ open · 2023Pooled it
- Downregulation of pigment epithelium-derived factor increases compensatory lung growth in mice after extended pneumonectomy.Pediatric research · 2026Article
- The WHO2SAFE Score: A Predictive Tool for Postoperative Oxygen Requirement After PACU Recovery.Journal of clinical medicine · 2025Article
- Maternal nutrition and offspring lung health: sex-specific pathway modulation in fibrosis, metabolism, and immunity.Food & nutrition research · 2025Article
- Pulmonary inflammation and immune responses induced by nanocellulose: Insights fromCurrent research in toxicology · 2025Article
- Do Ultrasound Lung Abnormalities Correlate to Biomarkers and Male Gender in Rheumatoid Arthritis Patients? A Monocentric Cross-Sectional Study.Journal of clinical medicine · 2024Article
- Modelling lung infection with Klebsiella pneumoniae after murine traumatic brain injury.Journal of neuroinflammation · 2024Article
- Combined repetitive inhalant endotoxin and collagen-induced arthritis drive inflammatory lung disease and arthritis severity in a testosterone-dependent manner.American journal of physiology. Lung cellular and molecular physiology · 2024Article
- Camera-Based Respiration Monitoring of Unconstrained Rodents.Animals : an open access journal from MDPI · 2023Article
- Impacts of COVID-19 in Breast Cancer: From Molecular Mechanism to the Treatment Approach.Current pharmaceutical biotechnology · 2023Review
- Immunological aspects and gender bias during respiratory viral infections including novel Coronavirus disease-19 (COVID-19): A scoping review.Journal of medical virology · 2021Article
- Androgen receptor activation alleviates airway hyperresponsiveness, inflammation, and remodeling in a murine model of asthma.American journal of physiology. Lung cellular and molecular physiology · 2021Article
- Article
- Exposure to bisphenols and asthma morbidity among low-income urban children with asthma.The Journal of allergy and clinical immunology · 2021Article
- The Effects of Maternal Smoking on Pregnancy and Offspring: Possible Role for EGF?Frontiers in cell and developmental biology · 2021Article
- Chemocentric Informatics Analysis: DexamethasoneACS omega · 2020Article
- Impact of Ozone, Sex, and Gonadal Hormones on Bronchoalveolar Lavage Characteristics and Survival in SP-A KO Mice Infected withMicroorganisms · 2020Article
- Significant Unresolved Questions and Opportunities for Bioengineering in Understanding and Treating COVID-19 Disease Progression.Cellular and molecular bioengineering · 2020Article
- Sex related differences in the pathogenesis of organ fibrosis.Translational research : the journal of laboratory and clinical medicine · 2020Review
- May patients receiving 5-alpha-reductase inhibitors be in higher risk of COVID-19 complications?Medical hypotheses · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Numerous studies in humans and experimental animals have identified considerable sex differences in respiratory physiology and in the response of the lung to environmental agents. These differences appear to be mediated, at least in part, by sex hormones and their nuclear receptors. Moreover, animal models are increasingly used to study pathogenic mechanisms and test potential therapies for a variety of human lung diseases, many of which appear to be influenced by sex and sex hormones. In this article, data are summarized from studies of lung function and disease in which sex differences have been observed. Specific attention is paid to animal models of acute lung injury, nonallergic and allergic lung inflammation, and lung fibrosis. It is anticipated that continued investigation of the role of sex and sex hormones in animal models will provide valuable insight into the pathogenesis and potential treatments for a variety of acute and chronic human lung diseases.
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Registered trials
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