Evidence map›Paper›PMID 19933962›Full record

Trial reportArchives of internal medicine2009

Physician and pharmacist collaboration to improve blood pressure control.

Barry L Carter, Gail Ardery, Jeffrey D Dawson, Paul A James, George R Bergus, William R Doucette, Elizabeth A Chrischilles, Carrie L Franciscus, Yinghui Xu

3 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Archives of internal medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 148 papers, 24 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
148citing papers in PubMed, 24 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00201019 nacompletednot on this map

Improving Adherence to Blood Pressure Guidelines

TypeinterventionalSponsorUniversity of IowaRan2003 to 2009Enrolled623ConditionsHypertensionArmsPhysician-pharmacist collaborative intervention
NCT02919033 naunknown statusnot on this mapstarted 2016, after this paper: background citation

A Coordinated PCP-Cardiologist Telemedicine Model (PCTM) in China's Community Hypertension Care: Study Protocol for a Randomized Controlled Trial

TypeinterventionalSponsorXu LeiRan2016 to 2018Enrolled330ConditionsHypertensionArmsUsual care, Self-management, PCTM intervention
NCT03872856 nacompletednot on this mapstarted 2019, after this paper: background citation

Home Blood Pressure Monitoring Intervention for Self-Management of High Blood Pressure Among Alaska Native People

TypeinterventionalSponsorSouthcentral FoundationRan2019 to 2023Enrolled164ConditionsHypertensionArmsBP-ICAN
3 · Its place in the literature

Who cites it

148 citing papers in PubMed, 24 syntheses or guidelines pooled it.

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  3. Impact of patient care teams on blood pressure control in patients with hypertension: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
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  11. A Systematic Review of Network Studies Based on Administrative Health Data.International journal of environmental research and public health · 2020
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  13. Patient and public perspectives of community pharmacies in the United Kingdom: A systematic review.Health expectations : an international journal of public participation in health care and health policy · 2018
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  20. Review of services provided by pharmacies that promote healthy living.International journal of clinical pharmacy · 2012
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88 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Barry L CarterDepartment of Pharmacy Practice and Science, College of Pharmacy, University of Iowa, Room 527, Iowa City, IA 52242, USA. barry-carter@uiowa.edu
Gail Ardery
Jeffrey D Dawson
Paul A James
George R Bergus
William R Doucette
Elizabeth A Chrischilles
Carrie L Franciscus
Yinghui Xu

Funding

A collaborative model to improve BP control and minimize racial disparities-CCCR01HL091841 · NHLBI · UNIVERSITY OF IOWA · PI CARTER, BARRY L · 2009 to 2013
$4.7M
University of Iowa Older Adults CERTU18HS016094 · AHRQ · UNIVERSITY OF IOWA · PI CHRISCHILLES, ELIZABETH A · 2006 to 2010
$4.0M
Improving Adherence to Blood Pressure GuidelinesR01HL070740 · NHLBI · UNIVERSITY OF IOWA · PI CARTER, BARRY L · 2003 to 2007
$3.2M
AHRQ HHS 5U18 HS016094AHRQ HHS U18 HS016094NHLBI NIH HHS R01 HL070740NHLBI NIH HHS R01 HL091841
6 · The paper itself

Abstract

backgroundStudies have demonstrated that blood pressure (BP) control can be improved when clinical pharmacists assist with patient management. The objective of this study was to evaluate if a physician and pharmacist collaborative model in community-based medical offices could improve BP control.

methodsThis was a prospective, cluster randomized, controlled clinical trial with clinics randomized to a control group (n = 3) or to an intervention group (n = 3). The study enrolled 402 patients (mean age, 58.3 years) with uncontrolled hypertension. Clinical pharmacists made drug therapy recommendations to physicians based on national guidelines. Research nurses performed BP measurements and 24-hour BP monitoring.

resultsThe mean (SD) guideline adherence scores increased from 49.4 (19.3) at baseline to 53.4 (18.1) at 6 months (8.1% increase) in the control group and from 40.4 (22.6) at baseline to 62.8 (13.5) at 6 months (55.4% increase) in the intervention group (P = .09 for adjusted between-group comparison). The mean BP decreased 6.8/4.5 mm Hg in the control group and 20.7/9.7 mm Hg in the intervention group (P < .05 for between-group systolic BP comparison). The adjusted difference in systolic BP was -12.0 (95% confidence interval [CI], -24.0 to 0.0) mm Hg, while the adjusted difference in diastolic BP was -1.8 (95% CI, -11.9 to 8.3) mm Hg. The 24-hour BP levels showed similar effect sizes. Blood pressure was controlled in 29.9% of patients in the control group and in 63.9% of patients in the intervention group (adjusted odds ratio, 3.2; 95% CI, 2.0-5.1; P < .001).

conclusionsA physician and pharmacist collaborative intervention achieved significantly better mean BP and overall BP control rates compared with a control group. Additional research should be conducted to evaluate efficient strategies to implement team-based chronic disease management.

trial registrationclinicaltrials.gov Identifier: NCT00201019.

Indexed as

Interdisciplinary CommunicationPharmacistsPhysiciansAdultAgedAntihypertensive AgentsBlood PressureBlood Pressure Monitoring, AmbulatoryChronic DiseaseFemaleHumansHypertensionIowaMaleMiddle AgedOdds RatioAntihypertensive Agents

Identifiers

PMID19933962
PMCPMC2882170

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.