Evidence map›Paper›PMID 19933231›Full record

ArticleGenetics2009

Darwin and genetics.

Brian Charlesworth, Deborah Charlesworth

Abstract readHistorical Article
In one paragraph

Article in Genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. The sources of adaptive variation.Proceedings. Biological sciences · 2017
    Review
  8. Article
  9. Evolution across the Curriculum: Microbiology.Journal of microbiology & biology education · 2016
    Article
  10. The Amborella vacuolar processing enzyme family.Frontiers in plant science · 2015
    Article
  11. Article
  12. Article
  13. Plasticity-mediated persistence in new and changing environments.International journal of evolutionary biology · 2014
    Review
  14. Mendelian-mutationism: the forgotten evolutionary synthesis.Journal of the history of biology · 2014
    Article
  15. Article
  16. Review
  17. Ecological genetics of sex ratios in plant populations.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2010
    Article
  18. Genetics and the causes of evolution: 150 years of progress since Darwin.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Brian CharlesworthInstitute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh EH9 3JT, United Kingdom. brian.charlesworth@ed.ac.uk
Deborah Charlesworth

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Darwin's theory of natural selection lacked an adequate account of inheritance, making it logically incomplete. We review the interaction between evolution and genetics, showing how, unlike Mendel, Darwin's lack of a model of the mechanism of inheritance left him unable to interpret his own data that showed Mendelian ratios, even though he shared with Mendel a more mathematical and probabilistic outlook than most biologists of his time. Darwin's own "pangenesis" model provided a mechanism for generating ample variability on which selection could act. It involved, however, the inheritance of characters acquired during an organism's life, which Darwin himself knew could not explain some evolutionary situations. Once the particulate basis of genetics was understood, it was seen to allow variation to be passed intact to new generations, and evolution could then be understood as a process of changes in the frequencies of stable variants. Evolutionary genetics subsequently developed as a central part of biology. Darwinian principles now play a greater role in biology than ever before, which we illustrate with some examples of studies of natural selection that use DNA sequence data and with some recent advances in answering questions first asked by Darwin.

Indexed as

Evolution, MolecularSelection, GeneticAnimalsBiological EvolutionGeneticsHistory, 19th CenturyHumansSpecies Specificity

Identifiers

PMID19933231
PMCPMC2778973

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.