Evidence map›Paper›PMID 19932197›Full record

ReviewAgeing research reviews2011

Effect of aging on cellular mechanotransduction.

Miaozong Wu, Jacqueline Fannin, Kevin M Rice, Bin Wang, Eric R Blough

Abstract readReview
In one paragraph

Review in Ageing research reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 3 citations in OpenAlex.

  1. Evidence Supporting Conservative Scar Management Interventions Following Burn Injury: A Review Article.Journal of burn care & research : official publication of the American Burn Association · 2025
    Review
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  14. The cellular mechanobiology of aging: from biology to mechanics.Annals of the New York Academy of Sciences · 2021
    Review
  15. Article
  16. Review
  17. Article
  18. Mechanotransduction in Wound Healing and Fibrosis.Journal of clinical medicine · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Miaozong WuCell Differentiation and Development Center, Marshall University, Huntington, WV, United States.
Jacqueline Fannin
Kevin M Rice
Bin Wang
Eric R Blough
Marshall University · US

Funding

Aging, aortic stiffness, and intracellular signaling.R15AG027103 · NIA · MARSHALL UNIVERSITY · PI BLOUGH, ERIC RICHARD · 2006 to 2006
$172k
NIA NIH HHS R15 AG027103
6 · The paper itself

Abstract

Aging is becoming a critical heath care issue and a burgeoning economic burden on society. Mechanotransduction is the ability of the cell to sense, process, and respond to mechanical stimuli and is an important regulator of physiologic function that has been found to play a role in regulating gene expression, protein synthesis, cell differentiation, tissue growth, and most recently, the pathophysiology of disease. Here we will review some of the recent findings of this field and attempt, where possible, to present changes in mechanotransduction that are associated with the aging process in several selected physiological systems, including musculoskeletal, cardiovascular, neuronal, respiratory systems and skin.

Indexed as

Cell Physiological PhenomenaAgingAnimalsBone and BonesCardiovascular Physiological PhenomenaHumansJointsMechanotransduction, CellularMuscle, SkeletalNeuronsRespiratory Physiological PhenomenaSignal TransductionSkin Physiological Phenomena

Identifiers

PMID19932197
PMCPMC2888727
OpenAlexW1528231423

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.