ArticleThe International journal on drug policy2010
Methadone as HIV prevention: high volume methadone sites to decrease HIV incidence rates in resource limited settings.
Article in The International journal on drug policy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.
- HIV infection and risk of overdose: a systematic review and meta-analysis.AIDS (London, England) · 2012Pooled it
- HIV-Risk Behavior Among Adults with Opioid Use Disorder During 12 Months Following Pre-trial Detention: Results from a Randomized Trial of Methadone Treatment.AIDS and behavior · 2021Trial
- Therapeutic drug monitoring of protease inhibitors and efavirenz in HIV-infected individuals with active substance-related disorders.Therapeutic drug monitoring · 2011Trial
- Methadone treatment and associated health and social outcomes after a national manufacturing closure in Mexico: a longitudinal observational cohort study in Tijuana.Lancet regional health. Americas · 2026Article
- Delivering HIV-Positive Test Results via Phone: Who Never Answered? Correlates of Undelivered Reactive HIV Results in a U.S. National Cohort of Sexual and Gender Minority Individuals.AIDS and behavior · 2026Article
- Depression and its associated factors among people who use drugs attending the Methadone Treatment Clinic at Tumbi Hospital in Pwani, Tanzania: A cross-sectional study.PLOS mental health · 2025Article
- The impact of the 2014 military conflict in the east of Ukraine and the Autonomous Republic of the Crimea among patients receiving opioid agonist therapies.Journal of substance use and addiction treatment · 2024Article
- Challenges to Providing Integrated HIV Prevention in Substance Use Treatment Settings: Frontline Staff Perspectives on HIV and Sex-Related, Education, Communication and Stigma.Substance use & misuse · 2023Article
- Methadone initiation in a bridge clinic for opioid withdrawal and opioid treatment program linkage: a case report applying the 72-hour rule.Addiction science & clinical practice · 2021Article
- A qualitative study of emergency department patients who survived an opioid overdose: Perspectives on treatment and unmet needs.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2021Article
- Qualitative Analysis of Community Support to Methadone Access in Kenya.Substance use & misuse · 2021Article
- HIV testing and ART initiation in people who inject drugs and are placed on methadone in Kachin State, Myanmar.Public health action · 2020Article
- Methadone and buprenorphine pharmacokinetics and pharmacodynamics when coadministered with fostemsavir to opioid-dependent, human immunodeficiency virus seronegative participants.British journal of clinical pharmacology · 2019Article
- Methadone Matters: What the United States Can Learn from the Global Effort to Treat Opioid Addiction.Journal of general internal medicine · 2019Review
- Low barrier buprenorphine treatment for persons experiencing homelessness and injecting heroin in San Francisco.Addiction science & clinical practice · 2019Article
- Twenty years of the methadone treatment protocol in Ireland: reflections on the role of general practice.Harm reduction journal · 2019Review
- Prevalence of Coaddictions and Rate of Successful Treatment Among a French Sample of Opioid-Dependent Patients With Long-Term Opioid Substitution Therapy: The OPAL Study.Frontiers in psychiatry · 2019Article
- HIV, HBV and HCV in people who inject drugs and are placed on methadone maintenance therapy, Yangon, Myanmar.Public health action · 2018Article
- The Opioid Epidemic in Africa And Its Impact.Current addiction reports · 2018Article
- Opioid addiction, opioid addiction treatment, and HIV infection.Topics in antiviral medicine · 2018Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The link between injection drug use and HIV has been extensively described. Despite worldwide prevention efforts, injection drug use continues to be a risk factor for HIV transmission and both HIV and injection drug use continues to spread across the globe. Although methadone has demonstrated multiple health benefits including the reduction in injection drug use and HIV acquisition, the utilisation of methadone in many areas of the world remains one of secondary, rather than primary, HIV prevention. As a result, many who finally begin methadone enter treatment having accumulated medical and mental health problems as a result of delayed treatment. Rapid access to treatment and a more aggressive policy that realizes that methadone can help reduce opioid drug use is necessary if methadone is effectively going to act as primary HIV prevention. To delay access to methadone only increases the probability that the individual will acquire an infectious disease that is more costly to the individual in terms of morbidity and mortality and more costly to society as a whole.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.