ArticleThe Journal of clinical endocrinology and metabolism2010
Glucose intolerance in pregnancy and postpartum risk of metabolic syndrome in young women.
Article in The Journal of clinical endocrinology and metabolism, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 7 of them syntheses that pooled it.
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The trial behind it
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Who cites it
85 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Gestational diabetes mellitus and development of intergenerational overall and subtypes of cardiovascular diseases: a systematic review and meta-analysis.Cardiovascular diabetology · 2024Pooled it
- Risk of developing metabolic syndrome after gestational diabetes mellitus - a systematic review and meta-analysis.Journal of endocrinological investigation · 2021Pooled it
- Association between metabolic syndrome and gestational diabetes mellitus in women and their children: a systematic review and meta-analysis.Endocrine · 2021Pooled it
- Factors Associated with Gestational Diabetes Mellitus: A Meta-Analysis.Journal of diabetes research · 2021Pooled it
- Gestational diabetes and the risk of cardiovascular disease in women: a systematic review and meta-analysis.Diabetologia · 2019Pooled it
- Prevalence and risk factors of gestational diabetes mellitus in Asia: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2018Pooled it
- Metabolic syndrome risk after gestational diabetes: a systematic review and meta-analysis.PloS one · 2014Pooled it
- Effect of Treatment of Mild Gestational Diabetes on Long-Term Maternal Outcomes.American journal of perinatology · 2020Trial
- Parity and serum lipid levels: a cross-sectional study in chinese female adults.Scientific reports · 2016Trial
- Effect of a low glycaemic index diet in gestational diabetes mellitus on post-natal outcomes after 3 months of birth: a pilot follow-up study.Maternal & child nutrition · 2015Trial
- Trial
- Hypertension at 5 months postpartum in women with gestational diabetes.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026Observational
- Antenatal glycemic control in gestational diabetes and its association with postpartum glucose intolerance and weight retention.Clinics (Sao Paulo, Brazil) · 2026Article
- Gestational Diabetes and Incident Hospitalization for Cardiovascular Disease: A Nationwide French Cohort Study.Journal of the American Heart Association · 2025Article
- Long-term risk prediction of diabetes mellitus using the 100-g oral glucose tolerance test during pregnancy: Insights into test patterns, single abnormal values, and abnormal fasting glucose.Pregnancy (Hoboken, N.J.) · 2025Article
- Gestational Diabetes Mellitus: Mechanisms Underlying Maternal and Fetal Complications.Endocrinology and metabolism (Seoul, Korea) · 2025Review
- Women with a history of gestational diabetes mellitus present an accumulation of cardiovascular risk factors at age 46-A birth cohort study.Acta obstetricia et gynecologica Scandinavica · 2024Article
- Impact of postpartum weight change on metabolic syndrome and its components among women with recent gestational diabetes mellitus.Reproductive health · 2024Article
- Pros and cons of live kidney donation in prediabetics: A critical review and way forward.World journal of transplantation · 2024Review
- Prediction of postpartum prediabetes by machine learning methods in women with gestational diabetes mellitus.iScience · 2023Article
25 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
CONTEXT/
objectiveGestational diabetes mellitus (GDM) and even mild glucose intolerance in pregnancy are both associated with increased risks of developing type 2 diabetes and cardiovascular disease in the future. Because the metabolic syndrome also identifies patients at risk of type 2 diabetes and cardiovascular disease, we hypothesized that gestational dysglycemia may be associated with an unrecognized latent metabolic syndrome. Thus, we sought to evaluate the relationship between gestational glucose tolerance status and postpartum risk of metabolic syndrome. DESIGN/SETTING/
participantsIn this prospective cohort study, 487 women underwent oral glucose tolerance testing in pregnancy and cardiometabolic characterization at 3 months postpartum. The antepartum testing defined three gestational glucose tolerance groups: GDM (n = 137); gestational impaired glucose tolerance (GIGT) (n = 91); and normal glucose tolerance (NGT) (n = 259).
main outcome measureThe primary outcome was the presence of the metabolic syndrome at 3 months postpartum, as defined by International Diabetes Federation (IDF) and American Heart Association/National Heart Lung and Blood Institute (AHA/NHLBI) criteria, respectively.
resultsThe postpartum prevalence of IDF metabolic syndrome progressively increased from NGT (10.0%) to GIGT (17.6%) to GDM (20.0%) (overall P = 0.016). The same progression was observed for AHA/NHLBI metabolic syndrome (NGT, 8.9%; GIGT, 15.4%; and GDM, 16.8%; overall P = 0.046). On logistic regression analysis, both GDM (odds ratio, 2.05; 95% confidence interval, 1.07-3.94) and GIGT (odds ratio, 2.16; 95% confidence interval, 1.05-4.42) independently predicted postpartum metabolic syndrome.
conclusionsBoth GDM and mild glucose intolerance in pregnancy predict an increased likelihood of metabolic syndrome at 3 months postpartum, supporting the concept that women with gestational dysglycemia may have an underlying latent metabolic syndrome.
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