Evidence map›Paper›PMID 19926681›Full record

ReviewPhysical therapy2010

Novel patterns of functional electrical stimulation have an immediate effect on dorsiflexor muscle function during gait for people poststroke.

Trisha M Kesar, Ramu Perumal, Angela Jancosko, Darcy S Reisman, Katherine S Rudolph, Jill S Higginson, Stuart A Binder-Macleod

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Physical therapy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06459401 (Effects of an Overground Propulsion Neuroprosthesis in Community-dwelling Individuals After Stroke), which is not on this map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06459401 nacompletednot on this mapstarted 2021, after this paper: background citation

Effects of an Overground Propulsion Neuroprosthesis in Community-dwelling Individuals After Stroke

TypeinterventionalSponsorBoston University Charles River CampusRan2021 to 2022Enrolled10ConditionsStrokeArmsPropulsion Neuroprosthesis
3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it, 137 citations in OpenAlex.

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  12. Multi-Modal Sensing for Propulsion Estimation in People Post-Stroke Across Speeds.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2025
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Trisha M KesarDepartment of Physical Therapy, University of Delaware, Newark, Delaware 19716, USA.
Ramu Perumal
Angela Jancosko
Darcy S Reisman
Katherine S Rudolph
Jill S Higginson
Stuart A Binder-Macleod
University of Delaware · USMagee Rehabilitation Hospital · US

Funding

Fast Treadmill Training/Functional Electrical Stimulation to Improve WalkingR01NR010786 · NINR · UNIVERSITY OF DELAWARE · PI BINDER-MACLEOD, STUART A. · 2007 to 2011
$2.8M
MOTION ANALYSIS SYSTEM FOR STUDY OF HUMAN MOVEMENT DYSFUNCTION: PHYSICAL THERAPYS10RR022396 · NCRR · UNIVERSITY OF DELAWARE · PI SNYDER-MACKLER, LYNN · 2006 to 2006
$222k
NCRR NIH HHS S10 RR022396NCRR NIH HHS S10 RR022396-01NINR NIH HHS R01 NR010786
6 · The paper itself

Abstract

backgroundFoot drop is a common gait impairment after stroke. Functional electrical stimulation (FES) of the ankle dorsiflexor muscles during the swing phase of gait can help correct foot drop. Compared with constant-frequency trains (CFTs), which typically are used during FES, novel stimulation patterns called variable-frequency trains (VFTs) have been shown to enhance isometric and nonisometric muscle performance. However, VFTs have never been used for FES during gait.

objectiveThe purpose of this study was to compare knee and ankle kinematics during the swing phase of gait when FES was delivered to the ankle dorsiflexor muscles using VFTs versus CFTs.

designA repeated-measures design was used in this study.

participantsThirteen individuals with hemiparesis following stroke (9 men, 4 women; age=46-72 years) participated in the study.

methodsParticipants completed 20- to 40-second bouts of walking at their self-selected walking speeds. Three walking conditions were compared: walking without FES, walking with dorsiflexor muscle FES using CFTs, and walking with dorsiflexor FES using VFTs.

resultsFunctional electrical stimulation using both CFTs and VFTs improved ankle dorsiflexion angles during the swing phase of gait compared with walking without FES (X+/-SE=-2.9 degrees +/- 1.2 degrees). Greater ankle dorsiflexion in the swing phase was generated during walking with FES using VFTs (X+/-SE=2.1 degrees +/- 1.5 degrees) versus CFTs (X+/-SE=0.3+/-1.3 degrees). Surprisingly, dorsiflexor FES resulted in reduced knee flexion during the swing phase and reduced ankle plantar flexion at toe-off.

conclusionsThe findings suggest that novel FES systems capable of delivering VFTs during gait can produce enhanced correction of foot drop compared with traditional FES systems that deliver CFTs. The results also suggest that the timing of delivery of FES during gait is critical and merits further investigation.

Indexed as

Stroke RehabilitationAgedAnkle JointBiomechanical PhenomenaElectric Stimulation TherapyFemaleGaitGait Disorders, NeurologicHumansKnee JointMaleMiddle AgedStroke

Identifiers

PMID19926681
PMCPMC2802826
OpenAlexW2122045337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.